Surgeons can now identify non-functioning pancreatic neuroendocrine tumors at high risk for early recurrence preoperatively. Early recurrence occurred in 11% of patients, with a median disease-free survival of 16 months. Neoplastic venous thrombosis predicted a 71% chance of early recurrence; without it, patients with a KI-67 index ≥5% and tumor size ≥3 cm had a […]
Category: General Surgery
New AI Model Detects Perineural Invasion in Colorectal Cancer
This machine learning model improves detection of perineural invasion (PNI) in colorectal cancer, crucial for surgical outcomes. LightGBM model achieved an AUC of 0.996 in training, 0.935 in testing, and 0.918 in external validation across 430 samples. PNI correlates with higher T stage, increased lymph node metastasis, and more lymphovascular invasion. Adopting this model could […]
New model predicts poor outcomes in liver surgery for HCC
Surgeons now have a validated model to identify patients at high risk for early non-curative recurrence after liver resection for hepatocellular carcinoma (HCC), crucial for tailoring postoperative care. Early non-curative recurrence significantly increases overall survival risk (hazard ratio 5.39). Median survival drops from 178.6 months to just 34.7 months in early recurrence cases (p < […]
ICG Navigation Outperforms Conventional Technique for Hepatic Hemangioma
Using indocyanine green (ICG) fluorescence navigation in laparoscopic hepatectomy leads to better outcomes for hepatic hemangioma patients. Median blood loss: 100 ml (ICG) vs 200 ml (conventional), p < 0.001. Hospital stays shortened: 5.9 days (ICG) vs 7.1 days (conventional), p < 0.001. For patients with an Iwate score above 9, ICG significantly reduced operative […]
Liposomal Bupivacaine Beats Ropivacaine for Hemorrhoid Surgery
Liposomal bupivacaine provides superior pain relief compared to ropivacaine for patients post-hemorrhoidectomy. Patients receiving liposomal bupivacaine had consistently lower resting pain scores (median 0-2.0 vs 2.0-4.0, p<0.001). The need for rescue analgesics dropped significantly in the liposomal group (43.9% vs 83.3%, p<0.001). Consider using liposomal bupivacaine to enhance postoperative comfort and reduce opioid usage. Lower […]
Extended thromboprophylaxis cuts VTE rates in colorectal surgery
Extended thromboprophylaxis significantly reduces venous thromboembolism (VTE) risk after colorectal surgery without increasing bleeding complications. VTE rates were reduced to 0.56% with low molecular weight heparin (LMWH) and 0.22% with direct oral anticoagulants (DOAC), compared to no extended treatment. No major bleeding events differed between LMWH and DOAC groups at 90 days. For high-risk patients, […]
Surgical Resection Boosts Survival in HCC After Triple Therapy
Surgical resection significantly improves survival for hepatocellular carcinoma patients who reach complete response following triple therapy. One-, two-, and three-year survival rates post-surgery were 96.0%, 90.8%, and 90.8%, compared to 91.3%, 85.8%, and 73.1% for nonsurgical management. Patients who underwent surgery saw 70.9% achieve pathological complete response; however, the overall complication rate was 24.2%. Surgical […]
Next-gen camera control for cholecystectomy using mixed reality
A new head-mounted mixed reality platform could revolutionize cholecystectomy by improving camera control. Verbal instructions for camera assistants dropped from 15.3 to 0.2 per procedure. Mean operative time decreased from 74.8 to 66.0 minutes. This technology not only boosts efficiency but also enhances visualization and reliability in surgery. Camera movements were reduced by over 70%, […]
New CAD System Rivals Endoscopist Techniques for CRC
A computer-aided diagnosis system is showing promise for predicting deeply invasive colorectal cancer but still lags behind established methods. The CAD system achieved an overall diagnostic accuracy of 61.3%, with high confidence cases showing 95.3% accuracy. Compared to magnifying narrow-band imaging (m-NBI) and magnifying chromoendoscopy (mCE), the CAD system’s performance was inferior (p = 0.011 and p = 0.014, […]
Predictive nomogram reduces futile surgery in gallbladder cancer
Surgeons can now better identify patients who may not benefit from surgery for gallbladder cancer. 11.1% of patients experienced ‘futile surgery’ with a median survival of only 8.9 months. Those who received successful surgical intervention had a median survival of 88.7 months (p < 0.001). Incorporating this nomogram into preoperative decision-making may significantly reduce unnecessary […]