Research comparing the effect of esophagogastrostomy on the anterior and posterior walls of the gastric conduit in minimally invasive esophagectomy revealed that placing the anastomosis on the anterior wall resulted in a lower rate of delayed gastric emptying. Out of the 439 patients included in the study, those with anterior wall anastomosis experienced fewer complications, […]
Category: Upper Gastrointestinal Tract
Intraoperative and Postoperative Complications in Antireflux and Hiatus Hernia Surgery
A comprehensive cohort study of 4,301 patients undergoing antireflux and hiatus hernia surgeries in Australia revealed a 12.6% incidence of intraoperative complications and a 13.3% incidence of postoperative complications. Independent predictors of complications included the Charlson comorbidity index, hernia size, revisional surgery, and baseline anticoagulant usage. These risk factors had distinct complication profiles and their […]
Validated Clinical Score Predicts Gastroesophageal Reflux in Patients with Chronic Laryngeal Symptoms
A validated clinical score, the COuGH RefluX, has been developed to predict the likelihood of gastroesophageal reflux disease (GERD) in patients with chronic laryngeal symptoms. The score, based on cough, overweight/obesity, globus, hiatal hernia, regurgitation, and male sex, accurately stratifies patients as low or high likelihood of GERD. With a sensitivity of 79% and specificity […]
The Feasibility and Promising Results of Conversion Surgery for Esophageal Cancer with Distant Metastasis
A multi-institutional retrospective study investigated the clinical impact of conversion surgery for esophageal cancer with synchronous distant metastasis after induction therapy. Out of the 66 enrolled patients, distant lymph node metastasis occurred in 77%, while distant organ metastasis occurred in 23%. The study found that conversion surgery after chemotherapy or chemoradiotherapy is feasible and may […]
Older age does not contraindicate esophagectomy for cancer, but mortality increases
Age should not be a contraindication to esophagectomy for cancer treatment, according to the results of an international multicenter retrospective analysis. The study included 575 patients who underwent esophagectomy between 2007 and 2016 and found that postoperative mortality increased with age, from 2% in younger patients to 4.8% in older patients. However, disease-free and disease-related […]
Machine Learning Enhances Early Gastric Cancer Identification
The systematic review and meta-analysis found that machine learning-based models have greater performance in the identification of early gastric cancer (EGC) compared to non-specialist clinicians. The sensitivity, specificity, and summary receiver operating characteristic (SROC) of the machine learning models were higher than those of non-specialist clinicians. With the assistance of machine learning models, the diagnostic […]
Male Sex and Roux-en-Y Reconstruction: Risk Factors for Abdominal Surgical Infectious Complications in Gastric Cancer Patients
Male sex and Roux-en-Y reconstruction were identified as independent risk factors for abdominal surgical infectious complications (ASIC) after distal gastrectomy for gastric cancer. A post-hoc analysis of a randomized controlled trial (JCOG0912) found that male patients had a 2.364 times higher risk of developing ASIC, and those who underwent Roux-en-Y reconstruction had a 2.310 times […]
Flot chemotherapy regimen is the most appropriate treatment for elderly patients with resectable gastric cancer
Researchers conducted a retrospective study to compare the outcomes and safety of different chemotherapy regimens as perioperative treatment in elderly patients with resectable gastric cancer. They found that the Flot and DCF regimens were associated with longer overall survival compared to other regimens, with Flot showing the most significant improvement. Additionally, the DCF regimen had […]
Laparoscopic Gastrectomy Demonstrates Benefits in Reducing Complications
Researchers conducted a study to examine the influence of a randomized controlled trial (RCT) on the practice and outcomes of laparoscopic gastrectomy in the Netherlands. The RCT included 10 Dutch centers and compared laparoscopic to open gastrectomy. Data analysis showed that there was no significant effect on clinical outcomes within the RCT itself. However, nationally, […]
An Optimized Follow-Up Strategy for Esophageal Cancer Patients: Personalized and Cost-Effective Surveillance Protocols
Researchers conducted a cohort study involving 4688 patients with esophageal cancer to develop an optimized postsurgery follow-up strategy. By using recursive partition analysis and a random survival forest, patients were stratified into four groups based on pathological features, with surveillance strategies developed for each group. These strategies were validated and found to outperform mainstream guidelines […]