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Upper Gastrointestinal Tract

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World J Surg Oncol10 Jun 2024

Improved survival rates with laparoscopic gastrectomy for T4a gastric cancer

A meta-analysis comparing laparoscopic gastrectomy (LG) versus open gastrectomy (OG) for nonmetastatic T4a gastric cancer patients revealed significantly better disease-free survival (DFS) with LG (p = 0.027) and comparable overall survival (OS). LG also showed reduced hazard of cancer-related death and overall mortality compared to…

BJS Open10 Jun 2024

Improved Survival with Surgical Resection in Metastatic Oesophageal Cancer

Study suggests that surgical resection or multimodal therapy, including surgery, significantly improves overall survival in selected patients with metastatic oesophageal cancer compared to chemotherapy alone. Resection as an independent factor for favourable survival was confirmed, highlighting its feasibility as a treatment option. Prospective randomized studies…

J Gastrointest Surg7 Jun 2024

Factors Associated with Lymph Node Metastasis in Gastric Cancer

Researchers analyzed 5606 gastric cancer patients, identifying key risk factors for lymph node metastasis (LNM) in early gastric cancer (EGC). Significant predictors include female gender, lower tumor location, tumor size >2 cm, mixed and undifferentiated histologic types, t1b stage, ulceration, and lymphovascular invasion. A nomogram…

World J Clin Cases7 Jun 2024

Prognostic Model for Unresectable Gastric Cancer Liver Metastases

Study establishes a reliable nomogram model with five independent risk factors for gastric cancer liver metastases. The model accurately predicts patient prognosis, showing promising predictive accuracy and clinical benefit for outcome evaluation. Results demonstrate high area under the curve values at 1, 3, and 5…

Upper Gastrointestinal Tract6 Jun 2024

Indocyanine Green Fluorescence for Lymph Node Metastasis in Gastric Cancer

Indocyanine Green (ICG) fluorescence in laparoscopic subtotal gastrectomy for gastric cancer showed a sensitivity of 75.86% in detecting metastatic lymph nodes and 90.7% in identifying them. ICG-guided lymphadenectomy revealed higher fluorescent lymph node numbers in patients with metastases. The method offers high negative predictive value…

Eur Surg Res6 Jun 2024

Improved Surgical Outcomes with Thoracic Duct Visualization

Patent blue injection enhances intraoperative thoracic duct visualization during esophagectomy. In a pilot trial, the duct was visualized in 60% of patients, leading to significantly shorter operative times, fewer complications, and shorter hospital stays compared to controls. Although chyle leak rates did not significantly differ,…

Upper Gastrointestinal Tract5 Jun 2024

Anti-reflux mucosectomy reduces reflux symptoms in GERD patients

Anti-reflux mucosectomy (ARMS) effectively reduced reflux episodes and acid exposure in GERD patients unresponsive to PPI treatment. ARMS also decreased transient lower esophageal sphincter relaxations (TLESRs) and reflux symptoms without impacting esophageal distensibility. These findings support ARMS as a viable option for managing PPI-refractory GERD,…