Category: Upper Gastrointestinal Tract

Hiatal Hernia Repair Post-Laparoscopic RYGB: Short-Term Symptom Relief

Symptomatic hiatal hernia (HH) with pouch migration is a rare complication after laparoscopic Roux-en-Y gastric bypass (RYGB), and there is limited evidence on the utility of surgical repair. In this retrospective review of 44 patients who underwent isolated HH repair after previous RYGB, researchers found that common symptoms were dysphagia and reflux. Surgical repair resulted […]

Long-term tube feeding after minimally invasive esophagectomy helps prevent skeletal muscle loss

Long-term tube feeding intervention after minimally invasive esophagectomy was found to effectively prevent skeletal muscle loss and aid in preventing sarcopenia. The study compared short-term and long-term outcomes of tube feeding intervention in patients who underwent esophagectomy. While there were no significant differences in postoperative albumin levels, body weight, or psoas muscle area between the […]

Improved Diagnostic Workup and Delay in Treatment Start in Esophageal Cancer Patients Between Two Tertiary Centers

Comparative study between two tertiary centers in Europe reveals that the time interval from diagnosis to treatment differs significantly between the centers. The main reasons for these differences are the need for additional diagnostics and variations in referral routines. Gastroscopy was frequently repeated for further anatomical mapping. Clearer protocols, checklists, and guidelines can contribute to […]

Laparoscopic Transverse Abdominis Plane Block Reduces Operation Time and Cost in Pancreatectomy and Gastrectomy

The study compared the efficacy and efficiency of laparoscopic transverse abdominis plane block (lap-tap) versus ultrasound-guided tap (us-tap) in patients undergoing pancreatoduodenectomy and gastrectomy. The lap-tap group showed a significantly shorter median time to skin incision and a reduction in operation cost by $602 compared to the us-tap group. Pain control and opioid use were […]

Robotic gastrectomy leads to superior short-term outcomes compared to laparoscopic gastrectomy for elderly individuals with advanced gastric cancer

Results from a propensity score-matching study comparing robotic gastrectomy (RG) and laparoscopic gastrectomy (LG) revealed that RG is safe and feasible for elderly patients with advanced gastric cancer. The study found that RG was associated with less intraoperative blood loss, a faster postoperative recovery time, a greater number of lymph nodes dissected, and earlier initiation […]

Neoadjuvant Docetaxel-Based Chemotherapy Followed by En Bloc Resection: Effective Treatment for Locally Advanced Esophageal Adenocarcinoma with Comparable Survival Outcomes

Neoadjuvant docetaxel-based chemotherapy followed by en bloc resection is an effective treatment for locally advanced esophageal adenocarcinoma. Results from a 15-year retrospective analysis showed that both docetaxel/cisplatin/5FU and 5FU/leucovorin/oxaliplatin/docetaxel regimens achieved similar survival outcomes. A high percentage of patients completed the neoadjuvant cycles, and the majority achieved an R0 resection. Although the median lymph node […]

Pathological Response is not a Reliable Surrogate for Overall Survival in Neoadjuvant Studies for Esophageal Cancer

The study evaluates the validity of using pathological response as a surrogate marker for overall survival (OS) in neoadjuvant studies for esophageal cancer. A meta-analysis comprising 40 trials and 55,344 patients shows that the surrogacy between pathological complete response (PCR) and OS is moderate. The study establishes a lack of surrogacy at the trial level […]

No Significant Hernia Recurrence, but Increased Complications: Impact of Smoking on Minimally Invasive Paraesophageal Hernia Repair Outcomes

The impact of active smoking on outcomes of minimally invasive paraesophageal hernia repair (PEHR) was assessed in this cohort study. There was no significant difference in rates of death or serious morbidity (DSM) or hernia recurrence between smokers and non-smokers. However, on further analysis using the National Surgical Quality Improvement Program (NSQIP) database, smoking status […]

Effect of Procedural Volume on Adverse Outcomes in Gastric Endoscopic Submucosal Dissection

A nationwide population-based study investigated the influence of procedural volume on the outcome of gastric endoscopic submucosal dissection (ESD) for gastric cancer or adenoma. The study included 88,687 patients who underwent 94,246 procedures between November 2011 and December 2017. The results showed that high- and medium-volume centers had a significantly lower risk of adverse outcomes […]

Neoadjuvant Chemotherapy Improves Survival in Diffuse Type Gastric and Gastroesophageal Junction Carcinoma

Multimodal therapy, specifically neoadjuvant chemotherapy, was associated with increased survival in patients with diffuse type gastric and gastroesophageal junction carcinoma, including signet ring cell carcinoma. All-cause mortality within 90 days postoperatively was lower after neoadjuvant chemotherapy compared to primary surgery. Additionally, mortality remained lower in the neoadjuvant chemotherapy group even after 90 days post-surgery. These […]