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Upper Gastrointestinal Tract

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J Gastrointest Surg22 Apr 2024

Hyperthermic Intraperitoneal Chemotherapy Improves Survival in Gastric Cancer Patients

Hyperthermic intraperitoneal chemotherapy (HIPEC) significantly improved overall survival and reduced recurrence rates in both prophylactic and therapeutic settings for peritoneal carcinomatosis of gastric origin. This systematic review and meta-analysis of randomized trials highlights the efficacy of HIPEC as a safe and effective tool for prophylaxis…

Surgical Endoscopy21 Apr 2024

High En-bloc and R0 Resection Rates in Esophageal Cancer

Esophageal cancer patients who underwent endoscopic submucosal dissection (ESD) for T1B tumors showed high en-bloc (100%) and R0 (82.3%) resection rates. Only 23.5% experienced tumor recurrence post-ESD, with safer outcomes in patients receiving additional therapies. Larger studies are necessary to confirm the long-term efficacy of…

Br J Surg20 Apr 2024

Prognostic Value of Cachexia Index in Oesophagogastric Cancer Patients

A novel prognostic marker, the cachexia index (cxi), is associated with disease progression, postoperative mortality, and overall survival in patients with locally advanced oesophagogastric cancer. Patients with low cxi had higher rates of disease progression, worse postoperative mortality, and decreased overall survival compared to those…

J Gastrointest Surg20 Apr 2024

Frailty and TG/PG Increase Risk of Postoperative Pneumonia in Gastric Cancer Patients

Frailty and total or proximal gastrectomy (TG/PG) were found to be independent risk factors for postoperative pneumonia (POP) in patients with gastric cancer undergoing gastrectomy. A simple risk assessment method combining these factors effectively predicted and prepared patients for POP, with a 5.5% incidence rate…

Upper Gastrointestinal Tract20 Apr 2024

Validation of Textbook Outcome Parameter in Esophageal Cancer Surgery

This study validates textbook outcome (TO) as a quality performance indicator (QPI) for esophageal cancer surgery. Postoperative complications, including Clavien-Dindo grade ≥3 complications, and 30-day readmission rate are associated with reduced survival. Updating TO parameters to include severe complications strengthens its association with increased survival,…

BMC Surg18 Apr 2024

Development of a Nomogram for Preoperative Estimation of Splenic Hilar Lymph Node Metastasis

A high-performing preoperative nomogram for predicting splenic hilar lymph node metastasis in non-greater curvature advanced proximal gastric cancer was developed. Tumor location, size, Borrmann type, and lymphadenectasis were key predictors. The nomogram showed good performance in both training and validation cohorts, aiding surgeons in making…

Surg Endosc16 Apr 2024

Laparoscopic Gastrectomy in Super-Geriatric Gastric Cancer

Geriatric patients with locally advanced gastric cancer who underwent laparoscopic gastrectomy had lower overall complication rates, shorter hospital stays, and less blood loss compared to those who underwent open gastrectomy. There was no significant difference in 3-year overall survival between the two groups, suggesting laparoscopic…