A retrospective analysis evaluated the effectiveness of the manual layered insertion anastomosis technique in reducing anastomotic leakage post-esophagectomy. The study included 56 patients who underwent this technique, all receiving minimally invasive esophagectomy. With no reported anastomotic leakages, the technique showed potential in reducing complications such as anastomotic stenosis and gastric acid reflux. The method’s efficacy […]

The Comprehensive Complication Index (CCI) showed a stronger positive association than the Clavien-Dindo Classification (CDC) with short-term postoperative complications in patients with gastric cardia adenocarcinoma. The CCI demonstrated superior correlation strength for hospital length of stay, duration of ICU stay, time to return to normal activities, and total hospitalization cost. These findings suggest that the […]

The study included 717 patients and found that the new muscle parameter, SMG, obtained by multiplying the skeletal muscle index (SMI) and skeletal muscle radiation attenuation (SMRA), can predict the prognosis of patients with gastric cancer. The findings showed that SMG can effectively predict both short-term outcome and long-term prognosis, suggesting its potential as a […]

Analysis of the SENORITA trial comparing laparoscopic standard gastrectomy (LSG) and laparoscopic sentinel node navigation surgery (LSNNS) for early gastric cancer (EGC) found that there was no significant difference in the 5-year disease-free survival (DFS), overall survival (OS), or disease-specific survival (DSS) between the two groups. Although gastric cancer-related events were more common in the […]

The main result of this study is that preoperative and postoperative serum CA19-9 values are independent risk factors for predicting the prognosis in patients with stage III gastric cancer after curative gastrectomy. Patients with CA19-9 levels greater than 35 U/ml had significantly lower recurrence-free survival and overall survival rates compared to those with CA19-9 levels […]

Gastroesophageal reflux disease (GERD) is a common condition with increasing prevalence worldwide and a high economic burden. Despite proton pump inhibitor (PPI) therapy, a significant number of patients remain symptomatic. This review highlights the importance of differentiating between unproven GERD and refractory GERD, and provides a comprehensive overview of the diagnostic workup and personalized management […]

Approximately 4-9% of patients had a tumor-positive resection margin after neoadjuvant chemoradiotherapy (ncrt) and esophagectomy. Only a small proportion of patients received adjuvant therapy, despite the association of positive margins with decreased survival. However, a real-world study revealed that 61% of patients were treated with adjuvant immunotherapy (specifically nivolumab) in 2021-2022. Notably, patients who underwent […]

Discontinuous growth (DG) in esophageal adenocarcinoma (EAC) is associated with adverse clinicopathologic features and worse patient outcomes. DG was found to be an independent adverse predictor of survival outcomes in EAC, even after adjusting for other factors such as tumor size and stage. This multi-institutional study highlights the significance of DG and emphasizes the need […]

Induction chemotherapy followed by response evaluation and esophagectomy in patients with advanced esophageal cancer showed promising results in terms of survival. A total of 238 patients were treated with taxane/platinum-based chemotherapy, with 64.7% undergoing surgical exploration. Resection was performed in 53.4% of patients, resulting in a median survival of 26.3 months and a 5-year overall […]