Esophageal cancer patients treated with neoadjuvant chemoradiation followed by esophagectomy were examined to identify high-risk predictors of residual carcinoma. The study found that the presence of stricture, positive biopsy, signet ring cell histology, and a maximum standardized uptake value (SUV max) >5.4 in the absence of esophagitis were associated with residual cancer. External validation confirmed […]

A multicenter study investigated the impact of surveillance after esophageal cancer surgery on recurrence patterns, treatment, survival, and quality of life. The study found that intensive surveillance was associated with reduced symptomatic recurrence, increased tumor-directed therapy, and improved overall survival for patients who underwent surgery alone and those with early-stage or favorable pathological stage cancer. […]

Thoracic duct (td) resection does not improve the prognosis of patients with esophageal cancer, according to a study analyzing 12,237 patients who underwent esophagectomy between 2007 and 2012 in Japan. The study found that td-resected patients had similar overall survival and cause-specific survival rates compared to td-preserved patients. However, td-resected patients had more retrieved mediastinal […]

Analyzing 120 elderly esophageal cancer patients (Stage I-IV), the study revealed a 5-year overall survival rate of 45.2%. Lower body mass index, reduced pre-albumin levels, advanced tumor stage, postoperative pulmonary issues, and specific treatments significantly influenced outcomes. Despite a median 31-month follow-up, esophagectomy proved safe and feasible for elderly patients, emphasizing the importance of preventing […]

Analyzing clinically node-negative gastric cancer patients, the study investigated the influence of time from diagnosis to surgery. Among 1824 patients, those with a longer interval (≥ 8 weeks) experienced less lymph node upstaging. Although overall survival differences appeared in Kaplan-Meier curves, multivariable analysis didn’t associate timing with survival. The findings suggest extended intervals don’t predict […]

In a prospective study on esophageal cancer patients undergoing thoracic esophagectomy, researchers compared tissue oxygen saturation and indocyanine green measurements. Tissue oxygen saturation imaging proved valuable in identifying the anastomotic site, overcoming limitations of indocyanine green. In 57 patients, decreased tissue oxygen saturation at the conduit tip correlated with congestion and an increased risk of […]

Examining 682 esophageal carcinoma cases, researchers found resecting metastatic lymph nodes (rm1ln) in stage IVB, especially in specific locations, showed feasibility and improved overall survival without compromising short-term safety. Notably, patients with rm1ln metastasis who underwent curative surgery demonstrated comparable short-term outcomes and overall survival to those without such metastasis. The study emphasizes the potential […]

Analyzing 1020 patients with gastric signet-ring cell cancer (GSRCC), researchers investigated the relationship between the number of examined lymph nodes (ELNs) and prognosis. X-tile analysis determined the optimal ELN cutoff as 22. Patients with more than 22 ELNs demonstrated higher 5-year overall survival (66.9% vs. 74.9%). Multivariate analyses revealed that a higher number of ELNs […]

Examining 115 elderly esophageal cancer patients, researchers assessed preoperative sarcopenia comprehensively using skeletal mass index, handgrip strength, and gait speed. Sarcopenia, identified in 20% of patients, correlated with older age and advanced cancer stage. Although postoperative complications showed no significant difference, slow gait speed was associated with more severe complications. The sarcopenia group exhibited significantly […]

A cohort study involving 205 gastric adenocarcinoma patients treated with neoadjuvant chemotherapy aimed to improve prognosis prediction. The developed radiomic model, incorporating pre- and post-treatment features, outperformed pathological T stage models. The final radiomic model, integrating radiomic and clinicopathological data, demonstrated superior accuracy in predicting 3-year survival. Results suggest the radiomic model could serve as […]