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Multimodal analgesia research shows rising global interest

A bibliometric analysis of multimodal analgesia (MA) research from 2013 to 2023 revealed a significant increase in publications, particularly post-2020, with 1,939 studies identified. The USA, China, and Canada emerged as leading contributors. Popular themes included non-steroidal anti-inflammatory drugs, enhanced recovery after surgery, and patient-controlled analgesia. Notable journals such as Cureus Journal of Medical Science and Anesthesia and Analgesia featured prominently, highlighting influential researchers like Richard D. Urman and Henrik Kehlet.

Journal Article by Jiang W, Qin Y and Chen L in Front Med (Lausanne)

Copyright © 2025 Jiang, Qin and Chen.

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High hospital volume reduces postoperative mortality after esophagectomy

A study examining 6,234 esophagectomy cases across 161 hospitals in Australia and New Zealand found a significant correlation between hospital surgical volume and in-hospital mortality. Mortality rates were lowest at 0.73% in high-volume hospitals performing 21 or more surgeries annually. In contrast, low-volume hospitals reported mortality as high as 5.71%. High-volume centers also demonstrated shorter hospital and ICU stays, emphasizing the importance of surgical centralization for improved outcomes.

Journal Article by Petric J, Ahmed M (…) Watson DI et 5 al. in World J Surg

© 2025 The Author(s). World Journal of Surgery published by John Wiley & Sons Ltd on behalf of International Society of Surgery/Société Internationale de Chirurgie (ISS/SIC).

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Interactive model enhances pancreas segmentation accuracy in CT images

A novel deep-learning network, RRM-TransUNet, significantly improves pancreas segmentation accuracy in CT images. Achieving a dice similarity coefficient of 93.82% and an average symmetric surface distance error of 1.12 mm on multiple datasets, this model integrates clinical expertise with user interaction. By using advanced techniques like rotary position embedding and a mixture of experts mechanism, RRM-TransUNet outperforms previous methods, providing clinicians with a more reliable and intuitive segmentation tool.

Journal Article by Wang Y, Liu W (…) Pan J et 2 al. in Int J Med Robot

© 2025 John Wiley & Sons Ltd.

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Microwave ablation matches surgical resection for liver metastases

In a cohort study involving 1,027 patients with colorectal liver oligometastases, survival outcomes between microwave ablation (MWA) and surgical resection (SR) were compared. After a median follow-up of 39.8 months, no significant differences were found in overall survival rates (MWA: 70.6 months vs. SR: 83.2 months) or progression-free survival (MWA: 18.5 months vs. SR: 22.3 months). The presence of 3-5 intrahepatic nodules and surgical resection were identified as independent risk factors for survival.

Comparative Study by Li B, Li L and Ren H in J Gastrointest Cancer

© 2025. The Author(s).

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Artificial intelligence enhances precision and safety in surgery

The integration of artificial intelligence (AI) in surgical medicine is revolutionizing the field, enhancing the precision and safety of procedures. AI aids in preoperative diagnosis, real-time navigation during surgery, and postoperative management. Specific case studies demonstrate significant improvements in surgical outcomes, such as reduced complications and faster recoveries. However, challenges including cost, data security, and the need for physician training remain barriers to widespread implementation. A systematic review highlights both the advantages and limitations of AI in surgical practice.

Review by Guo C, He Y, Shi Z and Wang L in Ann Med Surg (Lond)

Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.

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Arterial resection improves survival in pancreatic cancer patients.

A comparative analysis of 203 pancreatic cancer patients between 2010-2015 and 2016-2021 revealed significant improvements in outcomes due to multidisciplinary treatment. Patients in the latter group had higher preoperative chemotherapy rates (95%) and lower morbidity and pancreatic fistula rates. Overall survival notably improved, from 26.0 to 48.2 months, emphasizing the efficacy of radical resection, including arterial resection, for those with arterial involvement in pancreatic cancer.

Comparative Study by Hirose Y, Oba A (…) Takahashi Y et 13 al. in BJS Open

© The Author(s) 2025. Published by Oxford University Press on behalf of BJS Foundation Ltd.

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Successful implementation of enhanced recovery programs identified through contextual factors

A study identifies critical contextual factors for effective implementation of enhanced recovery programs (ERPs) in hospitals. Out of 86 hospitals, 30.2% achieved high ERP adherence. Success scenarios included low-socioeconomic status hospitals eager for change lacking team cohesion, low surgical volume hospitals with strong staff buy-in, and high-volume hospitals needing leadership support while ensuring appropriate workload. The findings underscore the importance of organizational readiness and support in enhancing surgical care outcomes.

Journal Article by Huang R, Remer SL (…) Ko CY et 5 al. in Ann Surg

Copyright © 2025 Wolters Kluwer Health, Inc. All rights reserved.

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Neoadjuvant chemotherapy improves survival in resectable pancreatic cancer.

Neoadjuvant chemotherapy using gemcitabine and S-1 significantly outperforms upfront surgery for patients with resectable pancreatic ductal adenocarcinoma (PDAC). In a randomized trial with 364 participants, median overall survival was 37.0 months for the chemotherapy group compared to 26.6 months for the surgery group, with a hazard ratio of 0.73. Additionally, median relapse-free survival was extended from 11.3 to 14.3 months. These findings underline the potential of neoadjuvant treatment in improving patient outcomes.

Journal Article by Unno M, Motoi F (…) Kosuge T et 12 al. in Ann Surg

Copyright © 2025 Wolters Kluwer Health, Inc. All rights reserved.

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Effective Implementation Strategies for Shared Decision-Making Identified

The systematic review reveals that implementing shared decision-making (SDM) in gastrointestinal cancer care faces challenges despite its importance for patient autonomy. Researchers synthesized data from 37 qualitative studies, identifying nine influencing factors categorized into two subthemes. Key strategies include enhancing medical staff’s understanding of patients’ needs and improving communication skills to facilitate SDM. These findings emphasize the necessity for healthcare professionals to actively engage with patients and their families to foster collaborative decision-making in treatment.

Review by Li M, Fu G (…) Li X et 3 al. in Ann Surg Oncol

© 2025. Society of Surgical Oncology.

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AI Model Outperforms Clinicians in Tumor Differentiation

An artificial intelligence model employing endoscopic ultrasonography (EUS) has demonstrated effective differentiation between small gastric stromal tumors (GSTs) and gastric leiomyomas (GLs). Utilizing a dataset of 358 EUS images, the ResNet50 architecture achieved impressive area under the curve (AUC) values of 0.994 and 0.911 for micro and small tumors respectively. In comparison, clinicians and clinical signatures yielded significantly lower AUCs, highlighting the model’s superior diagnostic capabilities and its potential as a pre-surgical decision-making tool.

Journal Article by Duan R, Duan L (…) Wei L et 3 al. in BMC Gastroenterol

© 2025. The Author(s).

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