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A new nomogram enhances prediction of postpancreatectomy hemorrhage

A novel nomogram has been developed to accurately predict late extraluminal postpancreatectomy hemorrhage (lepph) in patients with postoperative pancreatic fistula following pancreaticoduodenectomy. Utilizing a combination of key independent risk factors such as dorsal fluid accumulation and positive cultures in drainage fluid, the model demonstrated high predictive accuracy with c-index values of 0.932, 0.924, and 0.954 across three patient cohorts. This tool aims to facilitate timely interventions and improve patient outcomes.

Journal Article by Li Y, Zhang H (…) Tan C et 9 al. in Gland Surg

Copyright © 2025 AME Publishing Company. All rights reserved.

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A validated risk score predicts 90-day mortality after liver resection

A novel preoperative risk score predicts 90-day mortality after major liver resection, identifying five key risk factors: age ≥ 65 years, type 2 diabetes, a diagnosis of primary liver cancer, ASA ≥3, and extended hemihepatectomy. In a cohort of 513 patients, the 90-day mortality rate was 10.8%, with predicted rates of 3.5% for low risk, 11.1% for intermediate risk, and 29.7% for high risk patients. External validation confirmed the score’s reliability.

Journal Article by Ceuppens S, Olthof PB (…) Koerkamp BG et 21 al. in J Gastrointest Surg

Copyright © 2025. Published by Elsevier Inc.

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Surgical resection improves survival in colorectal lung metastases.

A retrospective analysis of 2,976 patients with solitary colorectal lung metastases revealed that surgical resection significantly enhances survival rates. Specifically, patients who underwent surgery had a five-year survival rate of 42.7%, compared to 29.7% for radiation therapy and 23.9% for conservative management. Multivariate analysis confirmed that surgical intervention was linked to improved survival outcomes (hazard ratio: 0.68). These findings support surgical resection as a viable option for select patients post-colon cancer treatment.

Journal Article by Arunachalam P, Chihara R (…) Kim MP et 2 al. in J Surg Res

Copyright © 2025 Elsevier Inc. All rights reserved.

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Incomplete resections lead to high rates of residual tumors

A significant 48.4% of patients undergoing salvage local resection (SLR) for incompletely resected rectal neuroendocrine tumors (r-NETs) had residual tumors. Rates varied by resection method: 70% for cold forceps polypectomy, 41.7% for conventional polypectomy/endoscopic mucosal resection, and 0% for modified techniques. Multivariate analysis indicated that suspected remnant tumors and the use of cold forceps were associated with higher residual rates, emphasizing the need for salvage resection in higher-risk cases to reduce recurrence chances.

Journal Article by Park JB, Kim GH (…) Yang DH et 10 al. in Dig Liver Dis

Copyright © 2025 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

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ERAS interventions enhance recovery in gastrointestinal tumor patients

A study found that enhanced recovery after surgery (ERAS) nursing interventions significantly improved postoperative outcomes for patients undergoing endoscopic resection of early gastrointestinal tumors. Compared to conventional care, patients in the ERAS group experienced lower complication rates, shorter hospital stays (4.8 vs. 6.3 days), and higher satisfaction and quality of life at three months. The results suggest that integrating ERAS principles into nursing protocols can optimize surgical recovery and patient well-being.

Randomized Controlled Trial by Shen Y, Xi Y, Ru LGX and Liu H in Langenbecks Arch Surg

© 2025. The Author(s).

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New diagnostic model effectively predicts microvascular invasion in HCC

A novel preoperative model for predicting microvascular invasion (MVI) in hepatocellular carcinoma (HCC) has been developed based on key clinical characteristics and serum biomarkers. Analyzing 1,027 patient cases, independent risk factors identified include hepatitis B virus infection, tumor size, and several alpha-fetoprotein markers. The model demonstrated strong diagnostic performance, with AUC values of 0.806 and 0.818 in development and validation cohorts, respectively, ensuring consistency with postoperative outcomes and promising clinical applicability.

Validation Study by Wang XQ, Fan YQ (…) Si YQ et 3 al. in J Invest Surg

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Alignment with Bologna guidelines improves outcomes in SBO patients

Compliance with the World Society of Emergency Surgery Bologna guidelines significantly enhanced outcomes for patients with adhesive small bowel obstruction (SBO). Among 982 patients, those receiving successful non-operative management (NOM) had a mean hospital stay of 5.3 days, while surgical interventions resulted in longer stays. Notably, optimal outcomes were achieved in 61% of successful NOM cases compared to only 16% in other treatment strategies. Only 17.2% of cases fully adhered to guidelines, illustrating the need for improved compliance.

Multicenter Study by Kaplan LJ, Martinez-Casas I (…) Bass GA et 4 al. in Br J Surg

© The Author(s) 2025. Published by Oxford University Press on behalf of BJS Foundation Ltd.
© The Author(s) 2025. Published by Oxford University Press on behalf of BJS Foundation Ltd.

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Gastropexy reduces recurrence rates of giant hiatal hernias.

In a study involving 77 patients with giant hiatal hernias, those undergoing anterior gastropexy experienced significantly lower recurrence rates of hiatal hernias and esophagitis compared to those without the procedure. Despite longer operating times for the gastropexy group, both groups showed no differences in post-operative complications. Symptom relief, including reductions in heartburn and reflux, was also markedly better in the gastropexy group. These findings support gastropexy as an effective intervention in improving surgical outcomes.

Journal Article by Fukushima N, Masuda T (…) Eto K et 8 al. in Surg Endosc

© 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Cholecystectomy improves symptoms in patients with gallbladder hyperkinesia

Cholecystectomy for patients with gallbladder hyperkinesia led to notable improvements, with 85% experiencing complete symptom resolution and 94% reporting partial improvement. A study involving 67 patients showed that those achieving complete resolution had a higher gallbladder ejection fraction (94%) compared to those without symptom resolution (88%). Most participants had abdominal pain, with additional symptoms like nausea and chronic diarrhea noted. The findings suggest that cholecystectomy may be beneficial beyond the traditionally accepted indications of gallbladder hypokinesia.

Journal Article by Hubbard GB, Prusko RM (…) Gemma RA et 5 al. in Am Surg

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Surface microdialysis effectively monitors liver metabolism post-surgery

A novel surface microdialysis probe demonstrated safety and feasibility for monitoring liver metabolism after resection in 17 patients. Complications were minimal and consistent with Clavien-Dindo classification. Key metabolites, including glucose, lactate, and pyruvate, were analyzed, revealing significantly higher lactate in liver samples compared to plasma, particularly in ischemic areas. Notably, the lactate/pyruvate ratio correlated with subsequent increases in alanine aminotransferase, indicating potential for in vivo tumor metabolism assessment and early risk detection.

Journal Article by Löfgren N, Blind PJ (…) Hemmingsson O et 3 al. in HPB (Oxford)

Copyright © 2025 The Authors. Published by Elsevier Ltd.. All rights reserved.

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