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Circular skin closure significantly reduces surgical site infections

A systematic review and meta-analysis revealed that circular skin closure (CSC) markedly decreases the rate of surgical site infections (SSI) following stoma closure compared to primary sutures (PS). Researchers found that only 4% of patients using CSC developed SSI, in contrast to 27% in the PS group. This analysis, which included eight randomized controlled trials with 606 patients, advocates for the adoption of CSC due to its superior outcomes in lowering SSI rates post-surgery.

Comparative Study by Menegon Tasselli F, Pata F (…) Pellino G et 5 al. in Tech Coloproctol

© 2025. The Author(s).

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Statistical cure model developed for HBV-associated hepatocellular carcinoma

A novel risk-stratification model for statistical cure after hepatectomy in hepatitis B virus-associated hepatocellular carcinoma (HBV-HCC) reveals an overall cure probability of 21.2%. The study identified eight independent risk factors, including high viral load and macrovascular invasion, that significantly influence outcomes. Low-risk patients achieved a 30.3% initial cure rate, with a remarkable 95% probability of cure at 8.6 years, contrasting sharply with negligible probabilities in high-risk individuals.

Journal Article by Li YF, Yao LQ (…) Yang T et 18 al. in Ann Surg Oncol

© 2025. Society of Surgical Oncology.

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Prehabilitation reduces postoperative pneumonia in esophagogastric surgery

A multimodal prehabilitation regimen improved postoperative outcomes for patients undergoing esophagogastric cancer surgery. Of 94 participants analyzed, those who completed at least 2 weeks of structured prehabilitation showcased a significant reduction in postoperative pneumonia compared to the control group. This research underscores the importance of tailored prehabilitation strategies in enhancing recovery and addressing complications in surgical patients, demonstrating a measurable benefit linked to compliance with the preoperative program.

Journal Article by Perwaiz A, Gupta A (…) Chaudhary A et 2 al. in World J Surg

© 2025 International Society of Surgery/Société Internationale de Chirurgie (ISS/SIC).

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Optimal Pain Management After Surgery is Under Study

The CARES trial aims to determine the effectiveness and safety of analgesic regimens in postoperative pain management. Enrolling adults undergoing elective surgeries, participants are randomized to receive either NSAIDs or low-dose opioids, complemented by acetaminophen. The primary outcomes include patient-reported pain intensity and side effects within the first week post-surgery. Secondary outcomes will assess various factors over six months, addressing significant evidence gaps in postoperative analgesic strategies. Recruitment will continue until 2026.

Multicenter Study by Bicket MC, Ladha KS (…) Li Y et 7 al. in BMJ Open

© Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ Group.

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Extraperitoneal colostomy reduces complications after laparoscopic APR

A systematic review involving 1,002 patients revealed that extraperitoneal colostomy (EPC) significantly lowers the incidence of parastomal hernia compared to transperitoneal colostomy (TPC) after laparoscopic abdominoperineal resection for rectal cancer. The EPC technique also showed reduced rates of stoma retraction, prolapse, and overall stoma-related complications. Importantly, both approaches did not differ significantly in total operative time or colostomy creation duration, suggesting EPC may be a safer option for long-term colostomy care.

Journal Article by Jin X, Li Y, Chen B and Zheng B in Surg Laparosc Endosc Percutan Tech

Copyright © 2025 Wolters Kluwer Health, Inc. All rights reserved.

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Financial toxicity is prevalent among hepatopancreatobiliary cancer patients

An analysis of the National Health Interview Survey highlights significant financial toxicity among U.S. patients with hepatopancreatobiliary (HPB) cancers. Of 5.6 million adults, 10.1% delayed medical care due to cost, while 8.4% could not afford necessary treatment. Uninsured patients faced markedly higher odds of financial challenges, and non-white patients were also more likely to delay care. The findings suggest urgent need for targeted interventions to reduce financial burdens impacting patient care in this population.

Journal Article by Cwalina TB and Zheng DX in J Gastrointest Cancer

© 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Robotic pancreatoduodenectomy shows improved outcomes with surgeon experience.

A study assessed the learning curve of robotic pancreatoduodenectomy among a first-generation surgeon. It identified three phases: competency, proficiency, and mastery, with significant reductions in operative time and complication rates as experience increased. At 90 days, severe morbidity was 24% and mortality was 5.4%. Mastery led to improved lymph node harvest, margin status, and better surgical outcomes compared to proficiency despite longer operative times. Structured training could enhance the learning process and outcomes.

Journal Article by Napoli N, Ginesini M (…) Boggi U et 8 al. in BMC Surg

Copyright © 2025 Elsevier Inc. All rights reserved.

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Minimally invasive surgery enhances outcomes for liver resection

A retrospective analysis of 164 liver resections for primary intrahepatic lithiasis demonstrated that minimally invasive techniques, which increased to 60% of surgeries, significantly reduced morbidity and hospital stays compared to traditional open surgery. Key complications included a 16% rate of bile fistula and 30% of septic events. Long-term follow-up showed a 20% recurrence linked to incomplete stone clearance and biliary fistula, emphasizing the need for ongoing surveillance in this patient population.

Journal Article by De Rose AM, Taliente F (…) Giuliante F et 4 al. in BMC Surg

Copyright © 2025 Elsevier Inc. All rights reserved.

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Contact X-ray brachytherapy offers effective treatment for rectal cancer

A systematic review and meta-analysis reveals that contact X-ray brachytherapy (CXB) provides an 82% clinical complete response rate in rectal cancer patients, presenting a compelling alternative to radical surgery. With a 14% salvage surgery rate and 81% organ preservation, CXB demonstrates long-term disease control, particularly beneficial for stoma-averse and older patients. The findings suggest clinicians should incorporate CXB into discussions about treatment options for rectal cancer, highlighting its safety and effectiveness.

Review by Powell SG, Wyatt JNR (…) Myint AS et 11 al. in Eur J Surg Oncol

Copyright © 2025 The Authors. Published by Elsevier Ltd.. All rights reserved.

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Cholecystectomy effectively resolves symptoms in biliary dyskinesia patients

A study of 415 patients identified that 89 (21%) had biliary dyskinesia, primarily affecting younger women (median age 46, BMI 28). Abdominal pain was the most common symptom. Pathological evaluations showed chronic cholecystitis in 84% of cases. Importantly, all patients with biliary dyskinesia experienced symptom resolution after cholecystectomy, suggesting this procedure is a first-line treatment for those presenting with biliary symptoms without structural abnormalities on imaging.

Journal Article by Popover JL, Oulton ZW (…) Toomey PG et 8 al. in JSLS

© 2025 by SLS, Society of Laparoscopic & Robotic Surgeons.

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