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Left-Sided Colon Cancer Shows Better Survival Than Rectal Cancer Post-Hepatic Metastasectomy

Survival outcomes differed between left-sided colon and middle/low rectal cancer post-colorectal hepatic metastasectomy. Patients with left-sided colon cancer exhibited significantly better overall survival (OS) than those with middle/low rectal cancer, especially in the subgroup analysis of ras mutations. The study suggests that middle/low rectal cancer should not be grouped together with left-sided colon cancer in terms of OS following colorectal hepatic metastasectomy.

Journal Article by Yang JH, Lin WL (…) Teng HW et 14 al. in J Gastrointest Surg

Copyright © 2024. Published by Elsevier Inc.

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Whipple Over the Splenic Artery (WOTSA) as an Alternative to Total Pancreatectomy for PDAC

Whipple over the splenic artery (WOTSA) can replace most total pancreatectomies for ductal adenocarcinoma, offering similar complication rates but improved postoperative glycemic status and potentially better disease-free survival. Results show no reoperations required in the WOTSA group due to pancreas or spleen issues, with comparable operative outcomes to total pancreatectomy. Findings suggest WOTSA as a safe and effective alternative for central-located pancreatic ductal cell adenocarcinoma.

Journal Article by Kuo TC, Wu CH (…) Tien YW et 5 al. in Int J Surg

Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.

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Colorectal Carcinoma In Situ Can Metastasize and Recur

Colorectal carcinoma in situ can metastasize to lymph nodes and recur, challenging previous assumptions. Among 1069 patients, 0.46% experienced regional lymph node metastasis or recurrence, with cases identified during or after primary surgery. Distant metastases were also observed, emphasizing the need for careful assessment at diagnosis. This study highlights the importance of recognizing potential metastasis and recurrence to ensure optimal oncological outcomes.

Journal Article by Kim S, Shin JK (…) Cho YB et 5 al. in Clin Colorectal Cancer

Copyright © 2024 Elsevier Inc. All rights reserved.

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Diagnostic Accuracy of Ultrasonography and Non-Contrast Computed Tomography in Acute Appendicitis

Ultrasonography and non-contrast computed tomography show high accuracy in diagnosing acute appendicitis, reducing negative laparotomy rates without increased risks. Computed tomography is superior to ultrasonography. The study compared sensitivity, specificity, and accuracy of both methods, indicating CT as a valuable second-line tool. With proper utilization of these imaging techniques, clinicians can effectively diagnose appendicitis and provide appropriate treatment.

Observational Study by Das U, Sarkar AN, Barman DC and Pandit N in Ethiop J Health Sci

© 2023 Uddalok D, et al.

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Comparing Laparoscopic-guided vs Ultrasound-guided TAP Block in Cholecystectomy

Ultrasound-guided TAP block is often preferred, but laparoscopic-assisted TAP (LTAP) shows shorter administration time. Post-operative pain management, analgesic requirements, and nausea were similar between LTAP and ultrasound-assisted TAP (UTAP) groups. However, UTAP group had reduced nausea and vomiting instances. LTAP block is a viable alternative in the absence of ultrasound guidance, offering quick and efficient pain relief post-laparoscopic cholecystectomy.

Comparative Study by Uzunay NT, Mingir T (…) Kose E et 2 al. in Cir Cir

Copyright: © 2024 Permanyer.
Copyright: © 2024 Permanyer.

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Higher Chemotherapy Dose and Muscle Mass Improve Pancreatic Cancer Survival

Study finds higher relative dose intensity (RDI) of adjuvant S-1 chemotherapy and greater psoas muscle mass volume (PMV) linked to significantly improved 5-year overall and relapse-free survival rates in patients with resected pancreatic ductal adenocarcinoma. RDI emerges as an independent prognostic factor, with patients displaying high RDI and high PMV showing the best outcomes. Combining RDI and PMV enhances prognostic accuracy for pancreatic cancer survival.

Observational Study by Sakamoto T, Kishino M (…) Fujiwara Y et 8 al. in Medicine (Baltimore)

Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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Consensus Supports Robotic HPB Surgery for Minimally Invasive Indications

Robotic surgery in hepato-pancreatic-biliary procedures is feasible and valuable for minimally invasive indications. Expertise is crucial for safety, encompassing requirements for credentialing in robotics. Prioritized questions for future trials include prospective registries with validated outcome metrics. The consensus guidelines from the Robot4HPB conference highlight state-of-the-art expertise and encourage safe use and promotion of robotic procedures in HPB surgery.

Journal Article by Hobeika C, Pfister M (…) Clavien PA et 12 al. in Ann Surg

Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.

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Evolutionary Paths and the ‘Bad Apple’ Effect in Hepatocellular Carcinoma

An atlas of hepatocellular carcinoma revealed seven genetic evolutionary paths influencing patient clinical trajectories. Most notably, the ‘bad apple’ effect showed that the aggressive cell fraction within tumors predicted prognosis better than overall heterogeneity levels, reshaping how clinicians predict survival. This study highlights the importance of tumor evolution in prognosis post-surgery and suggests personalized therapies based on tumor profiles, emphasizing the need for multi-region sampling and integrating multi-omics biomarkers in therapeutic decision-making.

Journal Article by Chen J, Kaya NA (…) Chow PK et 47 al. in J Hepatol

Copyright © 2024. Published by Elsevier B.V.

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Preoperative Risk Factors for Early Postoperative Bleeding after Roux-en-Y Gastric Bypass Surgery

Preoperative risk factors, including age, gender, hypertension, and revisional bariatric surgery, are associated with early postoperative bleeding after Roux-en-Y gastric bypass. Further primary studies are needed to explore additional risk factors for this complication, aiding in patient risk stratification and optimization. Male gender was identified as a significant predictor of early postoperative bleeding, emphasizing the importance of considering these factors in preoperative assessments for patients undergoing Roux-en-Y gastric bypass surgery.

Meta-Analysis by Santos-Sousa H, Amorim-Cruz F (…) Sousa-Pinto B et 12 al. in Langenbecks Arch Surg

© 2024. The Author(s).

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Machine learning and deep learning in hernia surgery

Machine learning and deep learning technologies are increasingly utilized in hernia surgery, showing promise in predicting outcomes and identifying factors associated with postoperative complications. Thirteen studies from 2020 to 2023 were included, focusing on inguinal, ventral, and incisional hernias. These studies varied in population, types of models used, and outcomes predicted, showcasing the potential of artificial intelligence in improving abdominal core health through accurate predictions and risk identification.

Journal Article by Lima DL, Kasakewitch J (…) Malcher F et 4 al. in Hernia

© 2024. The Author(s), under exclusive licence to Springer-Verlag France SAS, part of Springer Nature.

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