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Postoperative outcomes favor pure IVc approach in laparoscopic caudate lobectomy

Researchers introduced an inferior vena cava (IVC) priority approach in laparoscopic caudate lobectomy, studying 21 patients with caudate hepatic tumors. Those who underwent the pure IVC approach had shorter hepatic pedicle clamping and operation times as well as shorter hospital stays compared to the combined approach group. The technique proved safe and feasible, emphasizing the importance of IVC dissection in laparoscopic caudate lobectomy.

Journal Article by Guo L, Zhu XY (…) Guo WX et 7 al. in Langenbecks Arch Surg

© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

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Mesh Repair Reduces Ventral Hernia Recurrence Rates Over Time

The study revealed that the 5-year recurrence rate after ventral hernia repair was greater than 40% and 70% in patients with and without mesh, respectively. Ventral hernia recurrence rates increased over time, emphasizing the need for close, long-term follow-up. Risk factors associated with higher odds of recurrence include higher body mass index, immunosuppressants, incisional and parastomal hernias, robotic approach, greater hernia width, and certain types of mesh. Conversely, factors like greater mesh width, myofascial release, and fascial closure were linked to lower recurrence rates.

Journal Article by Bhardwaj P, Huayllani MT, Olson MA and Janis JE in JAMA Surg

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Centralization of Cytoreductive Surgery Alone Improves Perioperative Outcomes for Colorectal Peritoneal Metastases

Centralization of cytoreductive surgery alone for colorectal peritoneal metastases improved 90-day postoperative mortality and failure-to-rescue rates. High-volume centers showed lower mortality rates compared to low-volume and no-hipec centers. After the Prodige 7 trial, there was a drastic decrease in cytoreductive surgery with hyperthermic intraperitoneal chemotherapy rates in cancer centers, while patients treated with cytoreductive surgery alone continued to be referred to expert centers.

Journal Article by Noiret B, Lenne X (…) Eveno C et 2 al. in Ann Surg Oncol

© 2024. Society of Surgical Oncology.

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Study finds longer time to surgery and black race associated with worse survival in thyroid cancer patients

Delaying surgery for papillary thyroid carcinoma (PTC) worsens survival, with longer times to surgery associated with poorer outcomes. Racial disparities persist, as black patients face worse survival independent of time to surgery and other factors. Non-Hispanic white patients have shorter median times to surgery compared to black and Hispanic patients.

Journal Article by Gillis A, Zmijewski P (…) Bhatia S et 4 al. in Am J Surg

Copyright © 2024. Published by Elsevier Inc.

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Bariatric surgery post-liver transplantation in Belgium: Significant weight loss and metabolic improvements observed with favoring sleeve gastrectomy.

Bariatric surgery post-liver transplantation in Belgium showed significant and sustained weight loss, resolution of metabolic dysfunction-associated liver disease, and favorable metabolic outcomes. Sleeve gastrectomy was the favored procedure, leading to improved clinical and biochemical markers. Despite a small sample size, the results suggest the safety and efficacy of bariatric surgery in liver transplant recipients.

Journal Article by Onghena L, Geerts A (…) van Nieuwenhove Y et 9 al. in Liver Transpl

Copyright © 2024 American Association for the Study of Liver Diseases.

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Total Pancreatectomy Reduces Complications in High-Risk Pancreatoduodenectomy

Completion pancreatectomy during pancreatoduodenectomy significantly reduces postoperative complications and mortality rates in high-risk patients. In a study of 139 patients, total pancreatectomy (TP) resulted in shorter hospital stays, lower risks of post-pancreatectomy hemorrhage, and a significant reduction in reoperation, postoperative pancreatic fistula, hemorrhage, and mortality rates compared to pancreatoduodenectomy. Implementing a risk-tailored strategy with TP as the chosen approach can be life-saving for high-risk patients undergoing pancreatic surgery.

Journal Article by Ailhaud A, Girard E (…) Chirica M et 7 al. in World J Surg

© 2024 The Authors. World Journal of Surgery published by John Wiley & Sons Ltd on behalf of International Society of Surgery/Société Internationale de Chirurgie (ISS/SIC).

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Pathologic Factors Associated with Postoperative Venous Thromboembolism Risk after Gastrointestinal Cancer Surgery

Pathologic factors, including T, N, and M stages, were found to be associated with a higher risk of 30-day postoperative venous thromboembolism after gastrointestinal cancer surgery. Specifically, T stage was associated with VTE in colorectal, pancreatic, and primary hepatic cancers, while N stage was linked to VTE in colorectal and pancreatic cancers. Acknowledging these associations is crucial for tailoring a more personalized approach to chemoprophylaxis.

Journal Article by Janczewski LM, Silver CM (…) Merkow RP et 5 al. in J Gastrointest Surg

Copyright © 2024 Society for Surgery of the Alimentary Tract. Published by Elsevier Inc. All rights reserved.

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Embryologically Defined Peripancreatic Compartments

Researchers identified embryologically defined peripancreatic compartments and fusion planes, demonstrating distinct pancreatic compartments with potential significance in pancreatic cancer resection. Through manual preparation of body donors, they tracked mesogastria remnants and peripancreatic spaces sealed off from surrounding units. By following avascular embryologic fusion planes, they defined pancreatic cancer fields and proposed applying the success of total mesometrial resection and total mesorectal excision to pancreatic resection.

Journal Article by Alvanos A, Bechmann I and Steinke H in Eur J Surg Oncol

© 2024 Published by Elsevier Ltd.

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Key Challenges Faced by Young Oncology Investigators

A survey of 121 healthcare professionals in 36 countries revealed that access to education, training, networking, and mentorship are key limiting factors for young clinical investigators in oncology. Participants under 40 years of age and from European countries were more involved in clinical trials, mainly funded by industry grants. Half of the respondents devote personal time to research without payment, and almost half lack an experienced mentor in their institution.

Journal Article by Vasileva-Slaveva M, Morales-Espinosa D (…) Altena R et 4 al. in Eur J Surg Oncol

© 2024 Published by Elsevier Ltd.

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Prognostic Nomogram for Intrahepatic Cholangiocarcinoma

Researchers developed and validated a prognostic nomogram for intrahepatic cholangiocarcinoma, incorporating hepatitis C, CA19, tumor extent, tumor size, LVI, positive lymph nodes, and TMB as predictive factors. The nomogram demonstrated high accuracy in predicting patient outcomes with a c-index of 0.78 for the training set and 0.68 for the validation set. High-risk patients identified by the nomogram had significantly lower overall survival and recurrence-free survival rates.

Journal Article by Chen G, Li S (…) Liang W et 2 al. in Am Surg

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