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Improved Overall Survival in Metastatic Adrenocortical Carcinoma with Surgical Management

Surgical management, including primary tumor resection alone or with metastasectomy, significantly improved overall survival (OS) in metastatic adrenocortical carcinoma (ACC) patients. Metastasectomy alone did not show a survival benefit. Primary resection with metastasectomy was associated with better OS compared to primary tumor resection alone. These findings suggest that selected patients with metastatic ACC may benefit from surgical intervention, but further research is needed for appropriate patient selection.

Journal Article by Passman JE, Amjad W (…) Wachtel H et 3 al. in World J Surg

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Personalized Postoperative Opioid Prescribing: Enhancing Efficacy Through In-Hospital Consumption Data

In this study, rule-based guidelines derived from in-hospital opioid consumption were compared to standard guidelines for postoperative opioid prescribing. Results showed that the rule-based guidelines, tailored to individual patient consumption, outperformed other approaches and were more effective in aligning prescribed opioids with actual post-discharge consumption. This suggests that utilizing in-hospital consumption data to guide opioid prescribing can lead to more personalized and optimized postoperative pain management strategies.

Journal Article by Beaulieu-Jones BR, Berrigan MT (…) Brat GA et 4 al. in J Am Coll Surg

Copyright © 2024 by the American College of Surgeons. Published by Wolters Kluwer Health, Inc. All rights reserved.

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Impact of Neoadjuvant Immunotherapy on Perioperative Outcomes in Esophageal Adenocarcinoma

Patients with locally advanced esophageal adenocarcinoma who received neoadjuvant immunotherapy (io) combined with chemotherapy showed similar perioperative outcomes compared to those who received neoadjuvant chemotherapy alone. Rates of overall and major complications, anastomotic leak, respiratory complications, hospital stay length, and mortality were comparable between the two groups. The addition of immunotherapy did not significantly alter short-term outcomes after esophagectomy.

Journal Article by Nevo Y, Tankel J (…) Ferri L et 5 al. in Ann Surg Oncol

© 2024. Society of Surgical Oncology.

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Does Splenectomy Enhance Results of Distal Pancreatectomy for Body Pancreatic Ductal Adenocarcinoma?

After assessing spleen-preserving distal pancreatectomy (SPDP) and distal splenopancreatectomy (DSP) for body pancreatic ductal adenocarcinoma, it was found that SPDP is associated with less postoperative morbidity and does not impair oncological outcomes. Propensity score matching balanced patient characteristics, showing that SPDP is a viable option for b-PDAC patients located at least 5 cm from the spleen hilum, potentially eliminating the need for splenectomy in these cases.

Journal Article by Codjia T, Hobeika C (…) Sauvanet A et 8 al. in Ann Surg Oncol

© 2024. Society of Surgical Oncology.

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Factors Associated with Financial Toxicity After Upper Gastrointestinal Cancer Surgery

Patients younger than 50 years, of non-white race, with annual income <$75,000, and credit scores <740 were more likely to experience financial toxicity after gastrectomy or pancreatectomy. Longer hospital stays, extended time off work for surgery, and lower credit scores were also associated with financial toxicity. Minimally invasive surgery was linked to lower financial toxicity risk. Predicting financial toxicity before surgery and using minimally invasive techniques may help reduce the financial burden on patients.

Journal Article by Hirata Y, To C (…) Ikoma N et 6 al. in Ann Surg Oncol

© 2024. Society of Surgical Oncology.

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Frequency of size increase in gastric leiomyomas is low

Most gastric leiomyomas are benign subepithelial tumors, with few becoming symptomatic or increasing in size. A retrospective review of 231 cases showed that only 2.4% experienced size increase, one of which was leiomyosarcoma. The majority remained stable, with resections confirming leiomyoma. Close monitoring may be sufficient for asymptomatic cases, but resection could be considered for those showing ulceration or size increase.

Journal Article by Park K, Ahn JY (…) Jung HY et 7 al. in Surg Endosc

© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Differentiating Risk Factors: FED vs. GERD

Patients with functional esophageal disorders (FED) are more likely to be non-Hispanic Asian, have an underweight BMI, chronic pain, insomnia, and allergic rhinitis. Conversely, patients with an overweight BMI and who use alcohol have a decreased risk for FED. These findings provide valuable information for clinicians to identify and screen patients with reflux symptoms for potential FED.

Journal Article by Sachar M, Wizentier M (…) Knotts R et 5 al. in Surg Endosc

© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Geriatric Nutritional Risk Index predicts postoperative infectious complications in older adults after emergency gastrointestinal surgery

The geriatric nutritional risk index (GNRI) was found to be a predictor of postoperative infectious complications in older adults after emergency gastrointestinal surgery. Low GNRI was associated with higher age, serum C-reactive protein levels, and sarcopenia proportion, as well as longer hospital stays. GNRI also had a positive correlation with skeletal mass index, suggesting its utility as a nutritional marker and sarcopenia-related parameter in this population.

Journal Article by Takano Y, Kobayashi Y (…) Hanyu N et 3 al. in World J Surg

© 2023 International Society of Surgery/Société Internationale de Chirurgie (ISS/SIC).

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Improved quality of life and successful outcomes in surgical management of right-sided colonic diverticulitis

Patients with right-sided colonic diverticulitis who underwent surgery showed satisfactory short and long-term outcomes, with no disease recurrence or colorectal cancer detected on colonoscopy. A significant improvement in quality of life (QOL) was observed at 24 months post-surgery. The study highlights the effectiveness of surgical management in improving QOL and achieving successful outcomes in patients with right-sided colonic diverticulitis.

Journal Article by Lauricella S, Brucchi F (…) Faillace G et 4 al. in World J Surg

© 2024 The Authors. World Journal of Surgery published by John Wiley & Sons Ltd on behalf of International Society of Surgery/Société Internationale de Chirurgie (ISS/SIC).

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How Navigator Nurse Implementation Improves Healthcare Service and Perioperative Results in Liver Resections

Navigator nurse implementation in liver resections led to reduced length of stay, fewer emergency room visits, and readmissions. Patients receiving counseling and postoperative follow-up from navigator nurses had faster functional recovery and discharge, especially those with complications and undergoing open surgery. The presence of navigator nurses was an independent predictor of shorter length of stay, particularly in cases of benign diagnosis and laparoscopic approach. Overall, the implementation of navigator nurses optimized healthcare service, benefiting complex patients.

Journal Article by Fermi F, Ratti F (…) Aldrighetti L et 5 al. in World J Surg

© 2023 The Authors. World Journal of Surgery published by John Wiley & Sons Ltd on behalf of International Society of Surgery/Société Internationale de Chirurgie (ISS/SIC).

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