Novel nomograms utilizing multimodal imaging features and clinical data were developed and validated for predicting disease-free survival after TACE-based downstaging therapy followed by surgical resection in unresectable HCC patients. The nomograms outperformed five major staging systems in risk stratification, offering more accurate prognostic information to guide individualized treatment strategies for patients at high risk of […]
Author: STITCHES Newsletter
Distinct Tertiary Lymphoid Patterns in Colorectal Cancer
Deciphering heterogeneous tertiary lymphoid structures (TLS) patterns in colorectal cancer revealed three clusters with different prognostic implications. High metabolic activity and stromal pathways linked to worse outcomes, while immune activation pathways indicated improved prognosis and better response to immunotherapy. A new TLScore based on 9 core genes showed potential for guiding treatment decisions, highlighting the […]
Dependent functional status as a risk factor for 30-day mortality after colectomy
Dependent functional status significantly increases the risks of mortality, pulmonary complications, sepsis, extended postoperative NPO/NGT use, non-home discharge, 30-day readmission, and longer hospital stays post-colectomy for volvulus. Identifying DFS as an independent risk factor emphasizes its impact on postoperative outcomes, enabling tailored preoperative assessments and care strategies for these at-risk patients. Journal Article by Li […]
Bariatric Intervention Improves Steatohepatitis
Bariatric intervention significantly reduced BMI and intrahepatic fat in patients with obesity, leading to improvements in histologic features of metabolic dysfunction-associated steatohepatitis. Nonalcoholic fatty liver disease activity score decreased significantly at various time points post-intervention. These findings suggest that bariatric intervention may be an effective alternative for obese patients with metabolic dysfunction-associated steatohepatitis unresponsive to […]
Decreasing Superficial and Deep Infections in Colorectal Surgery
A noticeable decline in rates of superficial and deep incisional infections has been observed from 2013 to 2020 in colorectal surgery, attributed to increased use of minimally invasive techniques. However, organ space infections have shown an upward trend during the same period. Adoption of minimally invasive approaches has significantly lowered the odds of surgical site […]
Synoptic Operative Report for Rectal Prolapse
International expert consensus on operative descriptors for rectal prolapse surgery was achieved through a Delphi process. A synoptic operative report was developed, including 16 key descriptors with over 70% consensus. This standardized reporting aims to enhance clinical communication, quality measures, and research in pelvic floor disorders. The survey involved 176 surgeons across different regions, establishing […]
Outcomes of Laparoscopic Revisional Sleeve Gastrectomy with Hiatal Hernia Repair
Analysis of revisional and conversional sleeve gastrectomy procedures with concurrent hiatal hernia repair showed increased operative time, risk of postoperative pneumonia, and readmission within thirty days for patients with hiatal hernia repair. Despite these findings, patients undergoing laparoscopic revisional or conversional sleeve gastrectomy with hiatal hernia repair did not experience higher risks of death, postoperative […]
Gender Impact on Survival in Small Intestinal Stromal Tumors
Male patients with small intestinal stromal tumors (SISTs) have a higher risk of mortality compared to females. Females exhibit superior overall survival and cancer-specific survival rates than males. Surgical intervention significantly improves survival outcomes in both genders. Gender, along with age, grade, TNM stage, surgery, and mitotic rate, serves as a predictive indicator for survival […]
Laparoscopic Ladd Procedure for Adult Intestinal Malrotation
Laparoscopic Ladd procedure is safe and effective for adult patients with intestinal malrotation, with over 90% experiencing symptom resolution and significant quality of life improvement post-surgery. Complications are low, and the majority would recommend the procedure to others. Results show symptom improvement in 78.6% of patients and quality of life enhancement in 85.7%. Laparoscopic Ladd […]
Enhanced Quality of Life and BMI Maintenance with Double Tract Reconstruction
Double tract reconstruction after proximal gastrectomy demonstrates improved quality of life and better postoperative BMI maintenance, compared to other reconstruction methods. Results show reduced postoperative reflux symptoms, anxiety, and enhanced swallowing ability in the dtr group. Additionally, double tract reconstruction shows satisfactory anti-reflux effects and potential improvements in patient well-being and nutrition status, presenting a […]