CRS + HIPEC provides significant benefits to HCC-PM patients, with 89.0% 1-year and 3-year OS rates. Some patients achieved prolonged PFS, enhancing treatment options for this challenging condition. Incorporating CRS + HIPEC into the treatment regimen is a strategic therapeutic choice for HCC-PM patients, supported by the study’s findings of extended survival outcomes. Journal Article […]
Author: STITCHES Newsletter
Predicting Biliary Complications in Liver Transplant Patients
Utilizing LASSO logistic regression, researchers identified key risk factors for biliary complications in end-stage hepatic alveolar echinococcosis patients post ex vivo liver resection and autotransplantation. A prognostic nomogram model incorporating age, bile duct dilation, portal hypertension, and resection segments showed good discrimination and accuracy. The model predicted biliary complications with an AUC of 0.818 and […]
Comparison of Malnutrition Screening Tools in Hospitalized Patients
Prompt identification of malnutrition among hospitalized patients is crucial. A study compared 5 screening tools based on GLIM criteria on 1,397 inpatients. Results showed GMS had highest sensitivity (87.40%) and NRS-2002, highest specificity (91.70%). MST aligned well with GLIM, emphasizing early diagnosis importance. Effective screening tools can improve treatment efficacy. Journal Article by Arslan S, […]
Preoperative ICG-R15 Testing Predicts Post-hepatectomy Liver Failure
Preoperative ICG-R15 testing effectively predicts post-hepatectomy liver failure (PHLF) following major liver resection. A retrospective review of 72 patients revealed that 38.9% experienced PHLF, with 33.3% being severity score B and 4.16% score C. Univariate and multivariate analyses identified future liver remnant, ICG-R15 levels, and blood transfusion as independent predictors of PHLF. These findings emphasize […]
Pathologic Complete Response and Survival Paradox in Locally Advanced Rectal Cancer
Pathologic complete response (PCR) after preoperative chemoradiation correlates with improved overall survival for locally advanced rectal cancer patients. While total neoadjuvant therapy (TNT) increases PCR rates, it does not improve overall survival. Patients achieving PCR after TNT have worse survival compared to those with chemoradiation alone. The route to achieving PCR may be a crucial […]
Impact of Fat Embolism on Trauma Patients
Study reveals fat embolism in trauma patients associated with higher mortality, complications, and costs. Fat embolism linked to younger age, higher healthcare resource utilization. Trends show rising mortality and hospitalization costs over time in fat embolism group. Early identification crucial to improve outcomes and resource allocation for trauma patients. Journal Article by Ali K, Cho […]
Sleeve Gastrectomy Promotes Type 2 Diabetes Remission
Significant weight loss and remission of type 2 diabetes mellitus were observed in patients post-sleeve gastrectomy. Patients exhibited low citrulline and high I-FABP levels preoperatively, which normalized postoperatively. The study found a positive correlation between the I-FABP/citrulline ratio and weight, BMI, glucose, insulin, and c-peptide levels. Sleeve gastrectomy not only improves enteroendocrine function but also […]
Intraoperative Hemodynamic Monitoring for Pancreatectomy
Advanced intraoperative hemodynamic monitoring combined with a clinical decision-making algorithm improved hemodynamic parameters during pancreatectomy, showing a 33.3% reduction in intraoperative hypotension, 31.6% increase in cardiac index, and 37.6% increase in stroke volume variation. Further investigation in larger studies is warranted to validate these findings. Journal Article by Galouzis N, Khawam M (…) Dull RO […]
Income Changes and Pancreatic Cancer Resection
Income changes do not significantly impact the rate of patients undergoing surgical resection for early-stage pancreatic cancer. A study including 23,968 patients from 173 counties across 11 states showcases an overall resection rate of 45.1%, which increased from 42.8% to 47.4% between the early and late time periods. Notably, disparities in surgical intervention between lower-income […]
Effective Treatment for End-Stage Hepatic Hydatid Disease
Two-step vascular exclusion and in situ hypothermic portal perfusion during liver resection proves safe and effective for patients with advanced hepatic hydatidosis. With minimal complications and reduced anhepatic time, this technique allows for successful surgical treatment, resulting in good postoperative recovery and shortened hospital stays. Overall, this approach demonstrates promising outcomes in managing end-stage hepatic […]