Liver histology has been found to predict liver regeneration and outcome in ALPPS (Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy). The study analyzed the influence of histological alterations during the first and second stages of ALPPS on the liver’s ability to regenerate. A histological risk score and tumor pathology score were developed […]
Category: HPB & Spleen
Robotic limited liver resections show superior perioperative outcomes compared to laparoscopic limited liver resections
Robotic limited liver resections (RLLR) demonstrated superior perioperative outcomes, including reduced operative time, blood loss, and open conversion rate, compared to laparoscopic limited liver resections (LLLR) for posterosuperior liver segments. These findings were consistent even in a subset analysis of patients with cirrhosis. Postoperative outcomes, such as readmission, morbidity, and mortality, were similar between RLLR […]
High variability in VTE risk across abdominal surgery procedures, impacting thromboprophylaxis decisions
The study conducted systematic reviews and meta-analyses to estimate procedure-specific risks of symptomatic venous thromboembolism (VTE) and major bleeding after various types of abdominal surgery. They found that the risk of VTE varied widely among different procedures, with laparoscopic cholecystectomy having the lowest median risk (
Nationwide Implementation and Outcomes of Minimally Invasive Distal Pancreatectomy
After a nationwide training program and randomized trial, researchers conducted a Dutch pancreatic cancer audit-based study on 1496 patients undergoing minimally invasive distal pancreatectomy (MIDP) and open distal pancreatectomy (ODP). MIDP implementation increased from 48.6% to 63.0%, with considerable variation between centers. In the late implementation period, MIDP demonstrated stable outcomes, while ODP was more […]
Increasing HCC Hospitalizations and Decreasing Mortality: A Rising Financial Burden on Healthcare
Hepatocellular carcinoma (HCC) inpatient hospitalizations have increased from 2011 to 2017, with a decrease in mortality rates. However, the financial burden on healthcare has significantly increased due to rising in-hospital costs. The study also highlights sepsis, acute renal failure, and gastrointestinal hemorrhage as common mortality risk factors. The findings emphasize the importance of early diagnosis […]
Differences in Pancreatic Cancer Treatment and Outcomes: USA vs. Ontario
Patients with pancreatic cancer in the USA and Ontario, Canada were compared in terms of treatment patterns and outcomes. The study found that US patients received more radiation and chemotherapy compared to Ontario patients. Multimodality therapy was also more common in the USA. Conversely, neoadjuvant chemotherapy was more frequent in the USA but uncommon in […]
The “Superior Mesenteric Artery First” Approach Shows Comparable Outcomes to Conventional Approach in Pancreaticoduodenectomy
A comparative study evaluated the short-term and long-term outcomes of the “superior mesenteric artery first” (SMA-first) approach versus the conventional approach in pancreatic ductal adenocarcinoma (PDAC) patients undergoing laparoscopic pancreaticoduodenectomy. The SMA-first approach demonstrated a higher number of harvested lymph nodes and a lower involvement of the superior mesenteric artery (SMA) margin. No significant differences […]
Robotic Resection for Perihilar Cholangiocarcinoma Shows Promising Short-term Outcomes
Robotic resection for perihilar cholangiocarcinoma is a safe and feasible approach with acceptable short-term clinical and oncological outcomes. In a multicenter study of 38 patients, the majority had Klatskin type-3 tumors. The median age was 72 years, and most patients underwent preoperative biliary drainage. The procedure had a median operative time of 481 minutes and […]
Perioperative Chemotherapy Linked to Superior Overall Survival in Patients with Colorectal Liver Metastases
Perioperative chemotherapy is associated with superior overall survival in patients with synchronous colorectal liver metastases. Resection of both the primary and metastatic sites is linked to better overall survival. The study also found that patients who received perioperative chemotherapy had significantly longer overall survival compared to those who had preoperative or postoperative chemotherapy alone. Additionally, […]
Optimal surgical techniques and accumulation of cases lead to improved outcomes in robotic pancreaticoduodenectomy
Researchers from a Japanese single center experience studied 76 cases of robotic pancreaticoduodenectomy (RPD) and found that the mean operation time decreased over time despite the involvement of new surgeons. They also observed a decrease in major complications from the early competency phase to the mastery phase. Additionally, optimization of the procedure, specifically the hanging […]