After the learning curve, robotic pancreatoduodenectomy (RPD) demonstrated improved oncologic outcomes in patients with pancreatic duct adenocarcinoma (PDAC) compared to open pancreatoduodenectomy (OPD). A retrospective analysis of 548 patients revealed that RPD had longer overall survival (33.2 months vs. 25.7 months) and disease-free survival (18.5 months vs. 14.0 months) than OPD. RPD also had a […]

A retrospective study of 199 patients with localized small- and large-cell pancreatic neuroendocrine carcinoma (pannec) found that resection was associated with improved overall survival, while adjuvant chemotherapy did not significantly impact survival. The study also revealed an increasing trend in the rates of resection and adjuvant treatment since 2011. Resected patients were younger, treated more […]

Researchers evaluated the correlation between successful patient-derived xenograft (PDX) engraftment and survival in pancreaticobiliary cancer. They implanted 384 PDX models and found a 41% engraftment rate. Successful engraftment was strongly associated with both recurrence-free survival and overall survival outcomes. Furthermore, successful PDX tumor generation occurred significantly earlier than clinical recurrences. These findings suggest that successful […]

The systematic review and Bayesian network meta-analysis compared outcomes of high-volume, medium-volume, and low-volume hospitals performing liver resections. The analysis included 20 studies and 248,707 patients. The results indicated a significant association between hospital volume and postoperative mortality, favoring high-volume hospitals. Patients from high-volume hospitals generally experienced lower mortality rates and shorter lengths of stay […]

The main result of this study is the identification of three main categories that influence the implementation of early mobilisation in pancreatic surgery: attitude towards early postoperative mobilisation, subjective norm, and perceived behavioural control. These factors, which include perceived advantages or disadvantages, impact from healthcare professionals, family members, and fellow patients, as well as knowledge, […]

Surgeons’ ability to accurately predict surgical margins following resection of colorectal liver metastases (CRLM) was evaluated in this study. The analysis included 190 preoperative and 190 postoperative assessments from 95 cases, comparing surgeon assessments to histopathologic assessment. Results showed that surgeons are inaccurate at predicting positive and close surgical margins, with low sensitivity and positive […]

Robotic Pancreatoduodenectomy in a patient with Type III Portal Annular Pancreas (PAP) was successfully performed using the hanging maneuver and indocyanine green (ICG) fluorescence imaging. The technique involved transecting the pancreas into the neck of the anteportal portion and stapling the retroportal portion after dissection and encircling with hanging tape. ICG fluorescence imaging confirmed the […]

Three randomized controlled trials have reported improved functional recovery after laparoscopic pancreatoduodenectomy (LPD) compared to open pancreatoduodenectomy (OPD). This monocentric retrospective cross-sectional study found that patients who underwent LPD had significantly higher quality of life scores, better pancreas specific health status, improved physical functioning, and fewer limitations in activities compared to patients who underwent OPD. […]

Researchers examined pancreatic cancer patients with long-term survival and found that a subgroup with normal levels of the biomarker CA19-9 had a significantly higher overall survival rate and 5-year survival compared to patients with high CA19-9 levels. This subgroup also had lower levels of circulating glucose and increased insulin expression. Glucose control was shown to […]