Category: HPB & Spleen

Cutting Costs and Boosting Recovery: Perioperative APPs Slash Readmissions in Hepatopancreatobiliary Surgery

Dedicated perioperative Advanced Practice Providers (APPs) substantially decrease readmissions by almost 50%, saving $900 per case. Financially self-sustaining with 113 to 139 annual cases, these APPs prove pivotal in optimizing outcomes, minimizing resource utilization, and cost savings for high-volume hepatopancreatobiliary centers. Journal Article by Smith SR, Blair CM (…) Sarmiento JM et 3 al. in […]

Decoding HCC Recurrence: LI-RADS Morphologic Type II Gets Risk Score Upgrade

Unraveling the mystery of early recurrence in hepatocellular carcinoma (HCC), researchers crafted a risk scoring system based on tumor morphology. Analyzing 124 patients, they pinpointed age, histological grade, AFP, and intratumoral hemorrhage as key factors. The scoring system accurately stratified patients into low and high-risk categories, offering clinicians a powerful tool. The high-risk group exhibited […]

New Subtypes in Intrahepatic Cholangiocarcinoma

Researchers classified intrahepatic cholangiocarcinoma (ICC) into perihilar and peripheral subtypes, revealing distinctive features and survival outcomes. Among 1264 patients, 84.3% were ICC-peripheral, while 15.7% were ICC-perihilar. The perihilar subtype exhibited aggressive characteristics and poorer survival than the peripheral subtype. Interestingly, ICC-perihilar behaved akin to bile duct carcinoma, while ICC-peripheral resembled primary liver malignancies. This novel […]

Robotic Surgery Linked to Lower Postoperative Infections and Shorter Hospital Stays in Pancreatoduodenectomy

In a retrospective study spanning 2013 to 2022, researchers delved into healthcare-associated infections (HAIs) post-pancreatoduodenectomy (PD). Among 2632 patients, HAIs decreased over time, especially in open PD (OPD). Robotic PD (RPD) exhibited significantly fewer HAIs (5.8% vs. 9.6% in OPD). RPD correlated with reduced infections, shorter hospital stays, and higher costs. Notably, attention should be […]

Gallbladder Polyps: Size Matters in Predicting Cancer Risk

In this cohort study on 438 patients with gallbladder polyps (GPs), the risk of gallbladder cancer was 0.7% for all polyps, escalating to 5.9% for those ≥10 mm. GP size emerged as the sole predictor of malignancy (p = 0.0001), with a 21 mm cutoff indicating cancer risk. Patient’s age, symptoms, number of polyps, and […]

Big Data Shapes Future of Hepatopancreatobiliary Cancer Surgery

In the realm of surgical oncology, randomized controlled trials (RCTs) often face recruitment and standardization challenges. This study dives into hepatopancreatobiliary (HPB) cancer surgery, spotlighting the pivotal role of large databases. While RCTs provide crucial evidence, big data steps in where they fall short. Beyond justifying current practices, this research maps the future of HPB […]

Cholangiocarcinoma Unveiled: Early-Onset Warriors’ Triumph

In the epic battle against cholangiocarcinoma, researchers scoured the SEER database (1975-2020) for insights. Early-onset warriors (EOC), comprising 274 out of 4037 fighters, emerged with a distinct profile—often non-white, intrahepatic warriors. Despite facing a more advanced enemy at diagnosis, EOCs defied the odds. They opted for surgery, radiotherapy, and chemotherapy, influencing their fate. Cox analysis […]

Strategic Growth: Portal Vein Boost for Liver Resection in Cholangiocarcinoma

When facing borderline resectable intrahepatic cholangiocarcinoma (ICC), inducing hypertrophy pre-resection is a game-changer. In this single-center study, researchers found that portal vein embolization (PVE) prepped the battleground without raising perioperative issues. Overall survival (OS) matched non-PVE cases, but additional risks (multifocal tumors, lymph node involvement) threw a curveball, slashing OS notably. The takeaway? PVE proves […]

Harmony in Hepatic Recovery: Gata3 and Ramp2 Balance Key to Vascular Reconstitution

Unveiling liver regeneration intricacies, this study decodes Gata3 and Ramp2’s role in hepatic-vascular revival post-surgery. These hepatocyte conductors fuel liver sinusoidal endothelial cell proliferation. Pedf and Vegfa, playing contrasting roles in endothelial migration, spice up the dance. Gata3 inhibitors emerge as potential superheroes against post-hepatectomy liver failure. Serum Pedf/Vegfa Index (SPVI) steps in as a […]