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HPB (Oxford)7 Jun 2024

Artificial intelligence predicts non-transplantable recurrence in hepatocellular carcinoma

Artificial intelligence models accurately predicted non-transplantable recurrence in hepatocellular carcinoma patients post-hepatic resection. An ensemble AI model showed high accuracy (AUC 0.751-0.858) with incorporation of postoperative factors. Radiologic tumor burden and microvascular invasion were key predictors. Patients with predicted recurrence had lower survival rates, highlighting…

World J Clin Cases7 Jun 2024

Prognostic Model for Unresectable Gastric Cancer Liver Metastases

Study establishes a reliable nomogram model with five independent risk factors for gastric cancer liver metastases. The model accurately predicts patient prognosis, showing promising predictive accuracy and clinical benefit for outcome evaluation. Results demonstrate high area under the curve values at 1, 3, and 5…

J Gastrointest Surg6 Jun 2024

Management and Prognosis of Ruptured Hepatocellular Carcinoma

Spontaneous rupture of hepatocellular carcinoma (RHCC) presents a life-threatening complication in 3-15% of patients with HCC. Recent studies show improved survival benefits with transcatheter arterial embolization followed by elective hepatectomy. Despite poor prognosis, active surveillance and multidisciplinary management strategies can enhance short- and long-term outcomes.…

Ann Surg Oncol5 Jun 2024

Improved Survival Prediction in Intrahepatic Cholangiocarcinoma

Preoperative CT radiomics of intrahepatic cholangiocarcinoma and peritumoral tissue enhances survival prediction. Combined with clinical data, the radiomic model achieves equivalent prognostic estimates compared to postoperative pathology. In a study of 215 patients, the addition of radiomic features led to a significant improvement in overall…

World J Gastroenterol5 Jun 2024

Combination Therapy Improves Survival in Early-Onset Pancreatic Cancer

Study on non-metastatic early-onset pancreatic cancer patients showed postoperative survival improvement with adjuvant therapy. Surgery followed by neoadjuvant and adjuvant therapy recommended for locally advanced cases. 1-year, 2-year, and 3-year overall survival rates were 84.3%, 51.5%, and 27.6% respectively. Findings suggest a positive impact of…

J Surg Oncol5 Jun 2024

Adjuvant Chemotherapy Benefits Post-Pancreaticoduodenectomy

Adjuvant therapy following pancreaticoduodenectomy for pancreatic adenocarcinoma shows improved overall survival. Patients who responded favorably to neoadjuvant therapy may not benefit from additional adjuvant treatment. Downstaging after neoadjuvant therapy is a key factor in determining the efficacy of adjuvant therapy post-surgery. The study highlights the…

J Hepatobiliary Pancreat Sci5 Jun 2024

Improved Recurrence Prevention with Anatomical Liver Resection for Hepatocellular Carcinoma

Anatomical liver resection (AR) significantly reduces local and early recurrence rates compared to nonanatomical liver resection (NR) in patients with solitary hepatocellular carcinoma (HCC) ≤5cm. AR group exhibited lower recurrence rates, improved overall survival, and fewer instances of early recurrence. NR was identified as an…

World J Surg Oncol5 Jun 2024

Middle Colic Artery: A Key Landmark in Laparoscopic Pancreatoduodenectomy

Exposing the middle colic artery (MCA) first in laparoscopic pancreatoduodenectomy allows for safe and efficient determination of the superior mesenteric artery (SMA), first jejunal artery (J1A), and inferior pancreatoduodenal artery (IPDA). An anatomical correlation study found that 90.9% of MCA started at 12-3 o'clock from…

Ann Surg Oncol3 Jun 2024

Chemoradiotherapy Post-Neoadjuvant Chemotherapy Boosts Survival in High-Risk Pancreatic Cancer

Adjuvant chemoradiotherapy post-multiagent neoadjuvant chemotherapy in pancreatic cancer patients enhances survival, especially for those with lvi+ or grade iii tumors. While initial unadjusted analysis showed shorter median survival with chemoradiotherapy, adjusted results indicated a 25% risk reduction in mortality. Notably, patients with grade iii or…

BMC Surg3 Jun 2024

Cost-effectiveness of Liver Resection Techniques

Laparoscopic liver resection proves most cost-effective with lower total costs and superior postoperative outcomes compared to open and robotic liver resection. Open liver resection incurs the lowest procedural costs, but highest hospitalization costs. Robotic liver resection has the highest total and procedural costs but reduces…