Complete liver splitting along the demarcation line induced higher portal vein pressure and more rapid future liver remnant hypertrophy than partial or ectopic liver splitting after portal vein ligation in a rat model. The portal hemodynamic alterations, rather than inflammatory cytokine release, played a significant role in accelerating liver hypertrophy. Extrahepatic organ injury, such as […]
Category: HPB & Spleen
Identifying Risk Factors for Postoperative Infection in Choledochoscopy for IHDs
Preoperative biliary obstruction and operation time were identified as significant risk factors for postoperative infection in choledochoscopy for intrahepatic bile duct stones. Biliary tract infections, particularly with Escherichia coli, were the main cause of postoperative infection. Biliary tract obstruction and body mass index were independent risk factors for postoperative biliary tract infection in this real-world […]
Association of Race/Ethnicity with Invasive Intraductal Papillary Mucinous Neoplasms
Patients of race/ethnicity other than white had significantly higher rates of invasive intraductal papillary mucinous neoplasms during surgical resection, with 20.5% of cases demonstrating invasion. Despite being younger and healthier, non-white patients had higher odds of invasive neoplasms, independent of clinicodemographic variables. Postoperative morbidity did not differ among racial/ethnic groups. This national cohort study highlights […]
Machine learning does not outperform expert-informed predictions for outcome after major liver surgery
Expert-informed prediction models and machine learning models both showed similar performance in predicting postoperative overall morbidity in liver surgery patients, with high variability and over/underprediction. There was no improvement in performance for major liver surgery patients, indicating that machine learning may not have clinical relevance for predicting postoperative outcomes at this stage. Journal Article by […]
Impact of Pancreatic Duct Topography on Surgical Outcomes in Pancreatic Cancer
Findings from a study on 105 patients who underwent Whipple’s procedure for pancreatic cancer revealed that inferior pancreatic duct topography was linked to higher rates of metastatic spread and tumor recurrence, as well as reduced overall and recurrence-free survival. Conversely, posterior pancreatic duct topography was associated with lower incidence of perineural sheet infiltration and improved […]
Isolated Hepatic Perfusion with Melphalan in Uveal Melanoma Liver Metastases: Survival and Health-related Quality of Life Results
Survival and quality of life outcomes in patients with uveal melanoma liver metastases treated with isolated hepatic perfusion were evaluated in a Phase III randomized controlled trial. Isolated hepatic perfusion led to significantly longer progression-free survival compared to standard care, but no significant difference in overall survival at 24 months. Patients receiving isolated hepatic perfusion […]
Robotic Pancreatoduodenectomy Found Safe and Effective in Nationwide Study
In a nationwide study comparing robotic and open pancreatoduodenectomy, 701 patients underwent the robotic procedure while 4447 had the open one with similar major complications, mortality rates, and pancreatic fistula outcomes. Robotic pancreatectomy had longer operating times but resulted in less blood loss, fewer infections, and shorter hospital stays, particularly in centers performing over 20 […]
Laparoscopic surgery is effective in diagnosing and treating atypical hepatic cystic echinococcosis type 1
At a tertiary center in China, 93 patients were diagnosed with simple hepatic cysts, but 16 of them were actually identified as atypical CE1. Laparoscopy confirmed CE1 in 14 of these cases, showing high diagnostic precision. High-frequency ultrasound was effective in detecting CE1, and laparoscopic surgeries were successful in treating these cases without recurrence. This […]
Median Arcuate Ligament Release Restores Normal Arterial Flow in Pancreatectomy Patients with Celiac Artery Compression
Median arcuate ligament release during pancreatectomy for celiac artery compression restores normal arterial flow, reducing the extent of compression and preventing complications. Preoperative computed tomography accurately identifies compression levels, with postoperative imaging showing a reduction in all patients, mainly with type b compression. Complications were low, primarily readmissions, and no liver dysfunction was reported. Journal […]
Advancements in Chronic Pancreatitis Management
Chronic pancreatitis is a result of repeated pancreatic inflammation leading to loss of function, causing symptoms such as abdominal pain and diabetes. The review highlights the latest research on diagnostic methods and treatment options, including genetic factors and surgical interventions for patients not responsive to medications. Promising clinical trials are ongoing to develop new medical […]