The study analyzed data from four randomized controlled trials to determine the significance of primary tumor sidedness (PTS) in early-stage colorectal cancer. The results showed that PTS had no impact on the risk of recurrence in stage II/III colorectal cancer. Treatment stratification based on PTS is unnecessary for early-stage colorectal cancer. However, PTS was significantly […]

For patients with high-risk T1 colorectal cancer, the need for additional surgery after local excision (LE) is uncertain. A study analyzed patients who had received LE between 2009 and 2016. Comparing those who received additional surgery and those who did not, researchers found that regional lymph node metastasis occurred in 7.7% of the surgery group. […]

The study analyzed 200 men and 200 women with fecal incontinence to compare the causes and physiological characteristics. Both genders showed urge incontinence as the most common type. Men displayed higher prevalence of anal fistula, history of anal surgeries, rectal tumors, and pelvic radiotherapy as etiological factors, while pelvic surgeries were more common in women. […]

Rectal neuroendocrine tumors (NETs) sized 1-2 cm were analyzed to identify predictive factors for lymph node (LN) metastasis and recurrence. The study found that a higher rate of LN metastasis was observed in larger-sized tumors, advanced T stage, lymphovascular invasion, perineural invasion, and high tumor grade. Tumor size and grade were identified as significant risk […]

Italian researchers conducted a national study involving 788 patients from 76 highly specialized colorectal surgery wards to analyze the approach to lymphadenectomy during laparoscopic right hemicolectomy (RH). The study reveals that while laparoscopic RH is the preferred surgical technique, there is no standardized approach to lymphadenectomy. The analysis highlights the stable trend in surgical techniques […]

Patients with locally advanced rectal cancer who experience significant downstaging after preoperative chemoradiation have better overall survival compared to those with true pathologic stage 0-1 disease treated with upfront surgery. This was determined through a retrospective review of the national cancer database, which included a study population of 59,884 patients. The findings suggest that response […]

The surgical approach to rectal cancer resection has evolved over the past decade, with an overall increase in minimally invasive surgery (MIS) techniques. The study analyzed data from four countries and found that the proportion of MIS varied between countries initially but became more consistent over time. The use of local excision showed inconsistent trends. […]

Patients with lymph node distribution detected during laparoscopic colectomy with Japanese D3 dissection were divided into two groups: those with central vessel metastasis (LND3 group) and those without (LND1/2 group). After adjusting for background factors, the study found that LND3-positive patients had a worse prognosis compared to LND1/2 patients. Additionally, adjuvant chemotherapy improved the prognosis […]