Study demonstrates that combining surgery with HIPEC significantly improves 5- and 10-year overall survival rates and relapse-free survival of LAMN perforation patients without impacting short-term outcomes. Analysis of 91 patients revealed higher survival rates in the HIPEC group compared to non-HIPEC group, highlighting the potential impact of this combined approach on patient outcomes. Research Support, […]
Category: General Surgery
Association between Lymph Node Status on FDG-PET and Prognosis in Esophageal Cancer Patients
Fluorodeoxyglucose positron emission tomography (FDG-PET) effectively predicts lymph node status and prognosis in patients with esophageal squamous cell carcinoma (ESCC) undergoing esophagectomy after neoadjuvant chemotherapy (NCT). Researchers reviewed data from 124 ESCC patients and found that FDG-PET pre- and post-NCT correlated significantly with pathological lymph node metastasis, with post-NCT assessments serving as an independent predictor […]
Modified Mesohepatectomy for Congenital Biliary Dilatation
Modified mesohepatectomy offers a safe and beneficial alternative to trisectionectomy for treating bilobar congenital biliary dilatation. It results in higher residual liver volume, lower parenchyma resection rate, reduced complications, and optimal long-term outcomes, making it a valuable option for patients ineligible for major hepatectomy or transplantation. Comparative Study by Jin S, Jiang N (…) Dong […]
Optimizing Perioperative Management in Acute Biliary Disease
Standardizing process in acute biliary disease, researchers identified modifiable factors impacting patients’ time to theater, intraoperative time, and time to discharge. Implementing a perioperative management protocol based on imaging selection, operative grade identification, and drain placement could lead to significant cost savings and improved patient outcomes. Journal Article by Tranter-Entwistle I, Eglinton T and Connor […]
Effectiveness of Hyperthermic Intraperitoneal Chemotherapy in Gastric Cancer
A meta-analysis of 16 randomized controlled trials with 1,641 patients assessed the efficacy of hyperthermic intraperitoneal chemotherapy (HIPEC) for treating and preventing peritoneal carcinomatosis in advanced gastric cancer. Surgery plus HIPEC improved overall survival in both prophylactic (HR 0.56) and therapeutic (HR 0.57) settings, with a 3-year mortality rate of 32% for the prophylactic HIPEC […]
Association Between Social Vulnerability and Outpatient Management of Symptomatic Cholelithiasis
Patients with symptomatic cholelithiasis from vulnerable regions are more likely to fail outpatient management, leading to recurrent ED visits. Socially vulnerable status, especially in terms of socioeconomic and minority groups, significantly increases the odds of management failure. Timely follow-up and elective cholecystectomy can help reduce overutilization of ED resources for these patients. Journal Article by […]
Long-term Efficacy of Imatinib Combined with Hepatic Resection for GIST Liver Metastases
Imatinib combined with hepatic resection significantly improves overall survival in patients with gastrointestinal stromal tumor liver metastases compared to imatinib monotherapy. Achieving no evidence of disease status through surgical intervention leads to prolonged overall survival, liver-specific progression-free survival, and progression-free survival. Age ≤60 years and combination therapy were independently associated with better outcomes. Journal Article […]
Computed Tomography Radiogenomics: Predicting Molecular Subtypes in Gastric Stromal Tumors
A combined model integrating clinical and contrast-enhanced computed tomography (CE-CT) features accurately predicts specific genetic mutations in gastrointestinal stromal tumors (GISTs). Researchers developed three models from data from 231 GIST patients, with the best model achieving high accuracy in predicting molecular subtypes. In the training cohort, the area under the curve (AUC) values indicated significant […]
Effect of Compression Time on Postoperative Complications in Stapled Hemorrhoidopexy
Longer compression time (2 minutes) before stapler firing in staple hemorrhoidopexy resulted in decreased postoperative bleeding compared to typical compression time (30 seconds). Typical compression time was associated with higher rates of bleeding, additional procedures, and fecal urgency. No significant differences were found in dehiscence and stenosis rates between the groups. Journal Article by Yoo […]
Factors Influencing Variation in Postoperative Opioid Prescribing
Prescribing variation after surgery is largely influenced by prescriber-level factors, with a significant proportion of unwarranted variation in opioid quantities identified. Unwarranted covariates associated with higher opioid quantities include race, insurance status, smoking history, discharge times, and prescriber type. Targeting prescribers through education and training may effectively reduce excessive postoperative opioid prescribing practices. Journal Article […]