Ann Surg13 Apr 2024
QoL is maintained, with high symptom burden, during neoadjuvant therapy for gastrointestinal cancers. Functional well-being scores were consistently lower, while social well-being scores were higher. Common symptoms included fatigue, insomnia, and anxiety. Patients emphasized anxiety, fear, and frustration in free-text journaling but highlighted the importance…
Ann Surg13 Apr 2024
Robotic gastrectomy shows comparable 3-year disease-free survival and overall survival rates to laparoscopic gastrectomy in patients with gastric cancer. Sensitivity analysis also demonstrates similar outcomes in advanced cases. Robotic gastrectomy is associated with less blood loss, lower conversion rate, and shorter hospital stays, making it…
Ann Surg13 Apr 2024
Minimum CA19-9 decrease of ≥40% and optimal decrease of ≥60% after induction chemotherapy are independent predictors for prolonged overall survival in patients with locally advanced pancreatic cancer, particularly when CA19-9 levels are elevated at baseline. These thresholds can guide treatment decisions during early response evaluation.
Ann Surg13 Apr 2024
This study establishes prioritized lists of operative procedures for simulation-based assessments in general surgery training, essential for competency-based programs. Through a Delphi consensus study, 21 and 16 procedures were identified as suitable for assessments at key training stages, aiding in trainee progression and end-of-training certification.…
Ann Surg13 Apr 2024
Older adults undergoing major elective surgery experience significant challenges with postoperative symptoms affecting their valued activities and well-being. Participants felt unprepared for the intensity and duration of symptoms, highlighting the need for support and education. Postoperative pain, gastrointestinal discomfort, and anxiety/stress were prominent issues. Assessing…
Ann Surg13 Apr 2024
Factors such as information-sharing practices, planning, and strong leadership support were associated with successful implementation of enhanced recovery pathways in hospitals. However, barriers such as pathway complexity and infrastructure posed challenges. Clinicians' positive beliefs and knowledge about pathways were key to achieving greater adherence to…
Ann Surg13 Apr 2024
Patients with high output chyle leaks post-esophagectomy benefited from early intervention, showing improved overall survival and shorter hospital stays. Non-operative and late interventional management were associated with increased mortality compared to prompt intervention. Early intervention reversed prognostic implications and led to outcomes similar to patients…
Ann Surg13 Apr 2024
A study comparing costs for 2 days vs. 5 days of postoperative antibiotics after appendectomy for complex appendicitis found that two days resulted in a statistically significant cost reduction. The difference in overall societal costs was - €625 in favor of the 2-day group, largely…
Am J Gastroenterol13 Apr 2024
Pancreatic cancer surveillance in high-risk individuals led to early diagnosis of pancreatic malignancies and premalignant lesions, with most cases found at baseline. Of the 156 participants with at least a 3-year follow-up or cancer-related events, 9 individuals had malignant or premalignant lesions, demonstrating the feasibility…
BMC Surg13 Apr 2024
Robot-assisted and laparoscopic pancreatoduodenectomy showed similar major morbidity and mortality rates in a pan-European cohort. However, laparoscopic approach was associated with shorter operation time and lower rates of postoperative complications, while robot-assisted approach had lower conversion rates and higher lymph node retrieval. The study highlights…