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General Surgery

Best Papers in General Surgery

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Ann Surg13 Apr 2024

Maintained Quality of Life During Neoadjuvant Therapy for GI Cancers

QoL is maintained, with high symptom burden, during neoadjuvant therapy for gastrointestinal cancers. Functional well-being scores were consistently lower, while social well-being scores were higher. Common symptoms included fatigue, insomnia, and anxiety. Patients emphasized anxiety, fear, and frustration in free-text journaling but highlighted the importance…

Ann Surg13 Apr 2024

Defining Optimal CA19-9 Response in Locally Advanced Pancreatic Cancer

Minimum CA19-9 decrease of ≥40% and optimal decrease of ≥60% after induction chemotherapy are independent predictors for prolonged overall survival in patients with locally advanced pancreatic cancer, particularly when CA19-9 levels are elevated at baseline. These thresholds can guide treatment decisions during early response evaluation.

Ann Surg13 Apr 2024

Developing Prioritized Lists for General Surgery Trainee Assessment

This study establishes prioritized lists of operative procedures for simulation-based assessments in general surgery training, essential for competency-based programs. Through a Delphi consensus study, 21 and 16 procedures were identified as suitable for assessments at key training stages, aiding in trainee progression and end-of-training certification.…

Ann Surg13 Apr 2024

Impact of Postoperative Symptoms on Older Adults’ Quality of Life and Recovery

Older adults undergoing major elective surgery experience significant challenges with postoperative symptoms affecting their valued activities and well-being. Participants felt unprepared for the intensity and duration of symptoms, highlighting the need for support and education. Postoperative pain, gastrointestinal discomfort, and anxiety/stress were prominent issues. Assessing…

Ann Surg13 Apr 2024

Factors Distinguishing Higher Performing Hospitals in Implementing Enhanced Recovery Pathways

Factors such as information-sharing practices, planning, and strong leadership support were associated with successful implementation of enhanced recovery pathways in hospitals. However, barriers such as pathway complexity and infrastructure posed challenges. Clinicians' positive beliefs and knowledge about pathways were key to achieving greater adherence to…

Ann Surg13 Apr 2024

Early Intervention for High Output Chyle Leak Improves Survival Following Esophagectomy

Patients with high output chyle leaks post-esophagectomy benefited from early intervention, showing improved overall survival and shorter hospital stays. Non-operative and late interventional management were associated with increased mortality compared to prompt intervention. Early intervention reversed prognostic implications and led to outcomes similar to patients…

Am J Gastroenterol13 Apr 2024

Effectiveness of Pancreatic Cancer Surveillance in High-Risk Individuals

Pancreatic cancer surveillance in high-risk individuals led to early diagnosis of pancreatic malignancies and premalignant lesions, with most cases found at baseline. Of the 156 participants with at least a 3-year follow-up or cancer-related events, 9 individuals had malignant or premalignant lesions, demonstrating the feasibility…

BMC Surg13 Apr 2024

Comparing Robot-assisted and Laparoscopic Pancreatoduodenectomy in a Pan-European Cohort

Robot-assisted and laparoscopic pancreatoduodenectomy showed similar major morbidity and mortality rates in a pan-European cohort. However, laparoscopic approach was associated with shorter operation time and lower rates of postoperative complications, while robot-assisted approach had lower conversion rates and higher lymph node retrieval. The study highlights…