Category: Upper Gastrointestinal Tract

Primary Surgeon Specialty Does Not Impact Postoperative Complications in Esophagectomy

Cardiothoracic surgeons and general surgeons perform the majority of esophagectomies, but differences in surgical techniques exist. This study analyzed data from 3,247 patients and found that cardiothoracic surgeons were more likely to use traditional minimally invasive or open approaches, while general surgeons favored robotic or hybrid approaches. However, after adjusting for risk factors, there were […]

Low inter-rater reliability and variability in assessing laparoscopic fundoplication with endoscopy

This study evaluated the inter-rater reliability and variability in assessing laparoscopic fundoplication using endoscopy. A total of 101 participants, including upper gastrointestinal surgeons and gastroenterologists, analyzed ten static endoscopic images post-fundoplication. The study found that overall accuracy was 76% for upper gastrointestinal surgeons and 69.9% for gastroenterologists. Upper gastrointestinal surgeons performed significantly better in certain […]

Improved Detection of Lymph Nodes in Esophageal Squamous Cell Carcinoma Using Indocyanine Green-Near-Infrared Fluorescence Imaging

Indocyanine green-near-infrared fluorescence imaging showed a 100% success rate and significantly improved the detection rate of lymph nodes in esophageal squamous cell carcinoma. Seven cases with lymph node metastases were all near-infrared positive, while near-infrared-negative nodes were nonmetastatic. The technique accurately identified sentinel lymph nodes and increased the number of resected mediastinal lymph nodes, suggesting […]

Risk-Scoring Model for Lymph Node Metastasis in T1b-T2 Esophageal Cancer

Researchers constructed and validated a risk-scoring model to predict lymph node metastasis in T1b-T2 esophageal cancer. Multivariate analysis identified primary site, tumor grade, tumor size, depth, and lymphovascular invasion as independent risk factors for lymph node metastasis. The risk-scoring model, based on these factors, showed good predictive accuracy in both the primary cohort and the […]

Learning curve affects long-term quality of life after McKeown minimally invasive esophagectomy

The study investigated the impact of the learning curve on the long-term quality of life (QoL) of esophageal cancer survivors who underwent McKeown minimally invasive esophagectomy (MIE). The results showed that patients in the experienced learning phase had better QoL outcomes, with significant improvements in functional scales and symptom scales related to respiratory and digestive […]

Identification of High-Risk Features for Residual Carcinoma in Esophageal Adenocarcinoma Patients

Esophageal cancer patients treated with neoadjuvant chemoradiation followed by esophagectomy were examined to identify high-risk predictors of residual carcinoma. The study found that the presence of stricture, positive biopsy, signet ring cell histology, and a maximum standardized uptake value (SUV max) >5.4 in the absence of esophagitis were associated with residual cancer. External validation confirmed […]

Impact of Surveillance on Oncological and Quality of Life Outcomes in Esophageal Cancer Patients

A multicenter study investigated the impact of surveillance after esophageal cancer surgery on recurrence patterns, treatment, survival, and quality of life. The study found that intensive surveillance was associated with reduced symptomatic recurrence, increased tumor-directed therapy, and improved overall survival for patients who underwent surgery alone and those with early-stage or favorable pathological stage cancer. […]

Thoracic duct resection does not improve survival in patients with esophageal cancer

Thoracic duct (td) resection does not improve the prognosis of patients with esophageal cancer, according to a study analyzing 12,237 patients who underwent esophagectomy between 2007 and 2012 in Japan. The study found that td-resected patients had similar overall survival and cause-specific survival rates compared to td-preserved patients. However, td-resected patients had more retrieved mediastinal […]

Outcomes of Esophagectomy in Elderly Patients with Esophageal Cancer

Analyzing 120 elderly esophageal cancer patients (Stage I-IV), the study revealed a 5-year overall survival rate of 45.2%. Lower body mass index, reduced pre-albumin levels, advanced tumor stage, postoperative pulmonary issues, and specific treatments significantly influenced outcomes. Despite a median 31-month follow-up, esophagectomy proved safe and feasible for elderly patients, emphasizing the importance of preventing […]

Optimal Timing for Gastric Cancer Surgery: Impact on Lymph Node Upstaging and Survival

Analyzing clinically node-negative gastric cancer patients, the study investigated the influence of time from diagnosis to surgery. Among 1824 patients, those with a longer interval (≥ 8 weeks) experienced less lymph node upstaging. Although overall survival differences appeared in Kaplan-Meier curves, multivariable analysis didn’t associate timing with survival. The findings suggest extended intervals don’t predict […]