In a prospective study on esophageal cancer patients undergoing thoracic esophagectomy, researchers compared tissue oxygen saturation and indocyanine green measurements. Tissue oxygen saturation imaging proved valuable in identifying the anastomotic site, overcoming limitations of indocyanine green. In 57 patients, decreased tissue oxygen saturation at the conduit tip correlated with congestion and an increased risk of […]
Category: Upper Gastrointestinal Tract
Resecting M1 Lymph Nodes Improves Outcomes in Advanced Esophageal Carcinoma
Examining 682 esophageal carcinoma cases, researchers found resecting metastatic lymph nodes (rm1ln) in stage IVB, especially in specific locations, showed feasibility and improved overall survival without compromising short-term safety. Notably, patients with rm1ln metastasis who underwent curative surgery demonstrated comparable short-term outcomes and overall survival to those without such metastasis. The study emphasizes the potential […]
Optimal Lymph Node Removal Improves Survival in Gastric Signet-Ring Cell Cancer
Analyzing 1020 patients with gastric signet-ring cell cancer (GSRCC), researchers investigated the relationship between the number of examined lymph nodes (ELNs) and prognosis. X-tile analysis determined the optimal ELN cutoff as 22. Patients with more than 22 ELNs demonstrated higher 5-year overall survival (66.9% vs. 74.9%). Multivariate analyses revealed that a higher number of ELNs […]
Comprehensive Preoperative Sarcopenia Evaluation Predicts Poor Prognosis in Esophageal Cancer Patients
Examining 115 elderly esophageal cancer patients, researchers assessed preoperative sarcopenia comprehensively using skeletal mass index, handgrip strength, and gait speed. Sarcopenia, identified in 20% of patients, correlated with older age and advanced cancer stage. Although postoperative complications showed no significant difference, slow gait speed was associated with more severe complications. The sarcopenia group exhibited significantly […]
Radiomic Model Enhances Gastric Cancer Prognostic Prediction After Neoadjuvant Chemotherapy
A cohort study involving 205 gastric adenocarcinoma patients treated with neoadjuvant chemotherapy aimed to improve prognosis prediction. The developed radiomic model, incorporating pre- and post-treatment features, outperformed pathological T stage models. The final radiomic model, integrating radiomic and clinicopathological data, demonstrated superior accuracy in predicting 3-year survival. Results suggest the radiomic model could serve as […]
Logica Trial’s Impact: Evolution of Laparoscopic Gastrectomy in the Netherlands
Analyzing data from the Logica randomized controlled trial (RCT) and the Dutch Upper Gastrointestinal Cancer Audit (DUCA), researchers explored the influence of the Logica RCT on laparoscopic gastrectomy practice in the Netherlands (2012-2021). While the Logica RCT showed no significant impact on outcomes, the DUCA nationally revealed a shift, indicating laparoscopic gastrectomy’s benefits, significantly reducing […]
Improved Outcomes: Neoadjuvant Chemotherapy in Elderly Locally Advanced Gastric Cancer Patients
Examining elderly gastric cancer patients (>75 years) in the U.S., this study, using propensity score matching, reveals that neoadjuvant chemotherapy (NAC) utilization increased from 2013 to 2019 (21% to 42.7%). After matching, 1958 patients showed that those receiving NAC experienced enhanced oncological outcomes following resection for locally advanced gastric cancer. The findings advocate for the […]
Prognostic Significance of Circumferential Radial Margin in Esophageal Cancer Resection
Examining esophagectomy outcomes for pathologic T3 esophageal cancer (n=519, 2000–2019), researchers categorized patients based on circumferential radial margin (CRM) involvement. CRM+ (tumor at CRM) correlated with shorter disease-free survival (DFS) and overall survival (OS) compared to CRM-. CRM-close (tumor >0 to 1 mm from CRM) showed similar outcomes to CRM-. After adjustments, College of American […]
Objective Hiatal Hernia Sizing: Enhancing Precision in Surgical Decision-Making
Investigating hiatal hernia (HH) size reporting, researchers compared subjective estimates with objective axial length measurements in 93 patients. While endoscopic subjective size allocations correlated with intra-operative decisions, axial length measurements significantly correlated with manometry results. Only one barium swallow report included an objective HH size measurement. Integrating axial length measurements into endoscopy reports is crucial, […]
In Distal Gastric Poorly Cohesive Carcinoma, Total and Subtotal Gastrectomy Yield Comparable 5-Year Outcomes
A European multicenter study comparing total (TG) and subtotal gastrectomy (SG) for antropyloric poorly cohesive carcinoma found no significant difference in 5-year overall survival (TG: 53.8%, SG: 53.0%) or disease-free survival (TG: 46.0%, SG: 45.3%). Despite similar baseline characteristics, TG showed higher postoperative complications. This study supports subtotal gastrectomy as a viable option, offering comparable […]