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Robotic glissonean approach enhances safety in liver resections.

The glissonean approach, combined with robotic surgery, significantly improves the safety and precision of liver segmental resections. This technique aids surgeons in identifying and controlling critical anatomical landmarks, promoting better outcomes. Detailed instructional videos highlight the stepwise method for managing glissonean pedicles, while tips on optimizing dissection and using advanced imaging techniques ensure effective surgical practices. This multimedia resource serves as a vital guide for clinicians integrating robotic hepatectomy into their routines.

Journal Article by Ielpo B, Burdio F (…) Anselmo A et 3 al. in Ann Surg Oncol

© 2025. Society of Surgical Oncology.

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Safe Same-Day and Short-Stay Stoma Closures Revolutionize Care

A recent analysis of 22,312 patients shows that same-day (0.9%) and short-stay (8.2%) stoma closure protocols significantly reduce overall morbidity compared to traditional inpatient stays (90.9%)—11.8%. Both expedited discharge methods demonstrate comparable safety outcomes, with the inpatient group experiencing higher reoperation rates. Despite evidence supporting these approaches, their adoption remains limited, highlighting potential for improved outpatient protocols guided by specific risk factors.

Journal Article by Ferrari D, Violante T (…) Larson DW et 7 al. in J Gastrointest Surg

Copyright © 2025. Published by Elsevier Inc.

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Neoadjuvant treatment leads to promising watch and wait outcomes in rectal cancer

A nationwide study reveals that 15% of patients with non-metastasized rectal cancer successfully utilized a watch and wait strategy after neoadjuvant treatment. Among those treated with chemoradiotherapy, 21% achieved favorable results, compared to just 7% for short-course radiotherapy. Organ preservation rates improved to 17% when local excisions were included. Data indicate better baseline performance and lower tumor stages in patients opting for watch and wait, with three-year survival rates of 81% for short-course and 95% for chemoradiotherapy groups.

Journal Article by Mens DM, Coebergh van den Braak RRJ (…) Olthof PB et 10 al. in Eur J Surg Oncol

Copyright © 2025 The Authors. Published by Elsevier Ltd.. All rights reserved.

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Radical resection significantly improves survival in gallbladder cancer

A study found that liver resection dramatically enhances 5-year overall survival rates in T2 and T3 gallbladder cancer patients. Those undergoing this procedure had a survival rate of 43.8% versus 26.7% for non-surgical counterparts. Furthermore, achieving four or more lymph nodes increased survival to 49.9%. Radical resection notably improved survival to 52.5%. Subgroup analysis showed even higher survival rates for T2a patients (72%) compared to T3 patients (15.5%) when liver resection was performed.

Journal Article by Paik KY, You DD (…) Lee SH et 3 al. in Eur J Surg Oncol

Copyright © 2025 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

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Pancreatic guidewire-assisted fistulotomy proves more effective

In a trial involving 194 patients facing difficult biliary cannulation, the pancreatic guidewire-assisted fistulotomy method achieved a significantly higher success rate of 93.8%, compared to 81.4% for the transpancreatic biliary sphincterotomy technique (p=0.01). Both techniques exhibited similar rates of adverse events, suggesting that fistulotomy is the preferred choice after failed cannulation attempts. The transpancreatic method was particularly associated with unsuccessful outcomes due to specific anatomical conditions.

Journal Article by Sadeghi A, Arabpour E (…) Zali MR et 3 al. in Indian J Gastroenterol

© 2025. Indian Society of Gastroenterology.

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Reliable prediction model for anastomotic leakage in rectal cancer

A new clinical prediction model offers reliable assessment for anastomotic leakage (AL) in rectal cancer surgery, based on a study of 3,765 patients. The model identified key risk factors, including gender, diabetes, preoperative chemoradiotherapy, and surgical parameters. With area under the curve (AUC) values of 0.818 and 0.815 for internal validation, and consistent calibration results, this model stands out as a practical tool for improving patient outcomes during the perioperative period.

Journal Article by Yi X, Chen C (…) Ouyang M et 3 al. in Surg Endosc

© 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Different surgical options show varying effectiveness for GERD relief

A meta-analysis involving 9,516 patients found that all surgical procedures for gastroesophageal reflux disease (GERD) significantly improved post-operative outcomes. Nissen fundoplication outperformed transoral incisionless fundoplication in reducing acid exposure and Demeester scores. However, Toupet fundoplication and magnetic sphincter augmentation provided superior symptom relief compared to other methods. These insights enhance understanding of various surgical anti-reflux techniques, highlighting the importance of individualized treatment approaches for GERD patients.

Journal Article by Tadé Y, Newman D, Walters RW and Nandipati KC in Surg Endosc

© 2025. The Author(s).

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Gastrointestinal motility agents improve recovery after colorectal surgery

Gastrointestinal motility agents significantly enhance recovery in patients after elective colorectal surgery, according to a systematic analysis of seven randomized controlled trials involving 849 individuals. Patients experienced accelerated gastrointestinal recovery by 1.01 days and reduced time to first bowel movement by 1.07 days. Importantly, safety outcomes, including rates of complications such as anastomotic leaks and readmissions, showed no significant differences. The findings suggest that incorporating these agents into enhanced recovery protocols could be beneficial.

Review by Gosavi R, Dudi-Venkata NN (…) Narasimhan V et 7 al. in Int J Colorectal Dis

© 2025. The Author(s).

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Key genes linked to colorectal cancer stemness identified

A recent study identified ten key genes associated with colorectal cancer (CRC) stemness, revealing their correlation with disease-free and progression-free survival. Using a machine learning model, researchers found that higher mRNA expression-based stemness indexes (mrnasi) correlated with improved clinical outcomes. Notably, CRC samples with lower mrnasi exhibited worse survival rates. This research highlights the potential for small-molecule compounds to target these genes and suggests new therapeutic avenues for improving CRC treatment outcomes.

Journal Article by Lu J, Zhang H (…) Wang X et 3 al. in Medicine (Baltimore)

Copyright © 2025 the Author(s). Published by Wolters Kluwer Health, Inc.

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Nomogram predicts primary liver cancer risk in liver cyst patients

A newly developed nomogram effectively predicts the risk of primary liver cancer (PLC) in patients with liver cysts, integrating CT imaging features and alpha-fetoprotein (AFP) levels. In a study involving 122 participants, higher AFP levels and specific CT characteristics were linked to PLC occurrence. The nomogram exhibited a mean absolute error of 0.020 and achieved an area under the curve of 0.829, indicating its potential as a valuable tool in clinical risk assessment.

Journal Article by Jin ZL and Zhao LJ in Medicine (Baltimore)

Copyright © 2025 the Author(s). Published by Wolters Kluwer Health, Inc.

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