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Patient characteristics significantly influence readmission rates after metabolic surgery

Key findings reveal that specific patient characteristics, including race, body mass index (BMI), diabetes, chronic obstructive pulmonary disease (COPD), gastroesophageal reflux disease (GERD), and therapeutic anticoagulation, are linked to elevated 30-day readmission rates following metabolic surgery. Notably, black and Hispanic patients showed increased odds of readmission, particularly for multiple readmissions. This large-scale analysis emphasizes the importance of these factors in counseling patients regarding same-day discharge, aiming to improve patient outcomes and mitigate hospital resource utilization.

Journal Article by Kachmar M, Gunaldo JM (…) Albaugh VL et 6 al. in Surg Endosc

© 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Sequential injection-electrocoagulation improves hemostasis in ESD.

A randomized controlled trial involving 69 patients demonstrated that the sequential injection-electrocoagulation method significantly reduced the median time to hemostasis during endoscopic submucosal dissection (17 seconds) compared to traditional electrocoagulation (22 seconds), with p < 0.001. The experimental method also yielded higher visibility scores (3.24 vs. 2.82; p < 0.001) and reduced muscle injuries compared to the control group. Notably, one case of perforation was recorded in the control group, highlighting increased risks with traditional methods.

Journal Article by Ma ZY, Yang Z (…) Fan CQ et 7 al. in Surg Endosc

© 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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MMR protein status aids personalized cancer treatment decisions

Findings emphasize the importance of mismatch repair (MMR) protein expression in tumors, linking it to microsatellite instability (MSI) and its implications for colorectal and endometrial cancers. Loss of MMR status signifies potential treatment strategies for patients, helping clinicians in tailoring interventions to individual tumor profiles. This understanding may lead to improved clinical outcomes and enhance strategies for addressing DNA replication errors common in certain cancers. Insights bolster the significant utility of molecular signatures in prognosis and therapy.

Review by Nomikos IN, Kosmas C and Gkretsi V in Am J Surg

Copyright © 2025 Elsevier Inc. All rights reserved.

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Gradient boosting model predicts liver metastasis in pancreatic neuroendocrine tumors.

A study utilizing data from 7,463 pancreatic neuroendocrine tumor (PanET) patients developed a gradient boosting machine (GBM) model, marking it as the most effective tool for predicting liver metastasis. The model achieved an AUC of 0.937 and an accuracy of 0.87, highlighting independent risk factors like T-stage, N-stage, and previous treatments. It culminated in a user-friendly web-based calculator to assist clinicians in making informed treatment decisions based on individual patient risk assessments.

Journal Article by Bi J and Yu Y in Front Med (Lausanne)

Copyright © 2025 Bi and Yu.

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Robotic-assisted surgeries improve outcomes in rectal resections.

A multicenter real-world study analyzed rectal resections in 829 patients, revealing notable outcomes for robotic-assisted surgeries. This group experienced shorter hospital stays, less blood loss, and fewer postoperative complications compared to laparoscopic and open surgery techniques, while also achieving lower rates of positive circumferential resection margins. However, robotic-assisted surgeries required longer operating times. Early administration of adjuvant treatment was also noted for patients in the robotic group, enhancing speed and potentially improving recovery times.

Multicenter Study by Ramakrishnan AS, Kothari J (…) Dahiya A et 14 al. in J Robot Surg

© 2025. The Author(s).

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Vagus nerve-preserving gastrectomy improves outcomes in early gastric cancer

A multicenter analysis involving 1,210 early gastric cancer patients revealed that vagus nerve-preserving gastrectomy enhances perioperative safety and postoperative quality of life. Patients experienced shorter hospital stays and fewer complications such as diarrhea and acid reflux. A validated 6-point risk assessment model, derived from key factors like tumor size and invasion depth, effectively categorized patients into high- and low-risk groups, guiding personalized treatment strategies and improving postoperative survival outcomes.

Journal Article by Wang X, Wang X (…) Deng J et 14 al. in BMC Surg

Copyright © 2025 Elsevier Inc. All rights reserved.

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Affordable and Realistic Surgical Training Models Developed

Surgical training is enhanced by newly developed low-cost, high-fidelity skin and intestine surrogates. Utilizing 3D printing and readily available silicone materials, these models significantly improve biomechanical accuracy compared to industry standards. Feedback from surgical residents at the University of Missouri School of Medicine highlights their effectiveness, with a cost reduction of over 90% compared to commercial options. This innovation paves the way for broader applications in anatomical models, enhancing accessibility and efficacy in surgical education.

Journal Article by Giraldo-Londoño O, Bettale C (…) Wheeler A et 2 al. in J Surg Res

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Osteopenia and osteosarcopenia forecast outcomes in gastrointestinal cancers.

A systematic review identified osteopenia as a significant prognostic factor for overall survival (OS) and recurrence-free survival (RFS) in gastrointestinal cancer patients, with pooled hazard ratios of 2.20 and 2.15, respectively. Patients with osteosarcopenia faced threefold higher mortality and increased recurrence risk, highlighted by pooled hazard ratios of 2.96 and 2.75. These findings underscore the importance of integrating musculoskeletal assessments into oncological care to enhance timely interventions and improve patient outcomes.

Systematic Review by Zou X and Wang Y in Front Med (Lausanne)

Copyright © 2025 Zou and Wang.

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Nomograms effectively predict long-term survival in metastatic colon cancer.

A population-based analysis of 6,857 patients with de novo metastatic colon cancer developed a nomogram to predict overall survival (OS) and cancer-specific survival (CSS). Key prognostic factors included histological grade, age, cancer stage, metastasis presence, perineural invasion, carcinoembryonic antigen levels, chemotherapy, and surgery. The nomogram showed a promising concordance index of 0.72, allowing for stratification into risk groups and providing personalized long-term survival probabilities for patients.

Journal Article by Wang R, Cheng J, Zhong W and Wang X in Ann Ital Chir

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Maximum constriction velocity predicts postoperative nausea and vomiting

In a study involving patients undergoing elective lobectomy, maximum constriction velocity (mcv) of pupils was identified as a strong independent predictor of postoperative nausea and vomiting (PONV). Those with higher mcv showed an 87% reduced risk of PONV, while gender impacted risk, with males having a 65% lower likelihood compared to females. Notably, mcv also influences postoperative recovery quality through its relationship with PONV, with a receiver operating characteristics area under the curve of 0.831 indicating strong predictive utility.

Observational Study by Zhang Y, Jin J (…) Shi C et 5 al. in Ann Ital Chir

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