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Quality of Life Thresholds in Crohn’s Disease

Study establishes quality of life thresholds using SIBDQ scores in Crohn’s disease patients, identifying a ‘resection red zone’ indicating surgery discussion need. Results show a worse SIBDQ score increases odds of bowel resection. SIBDQ enhances predictive value for surgery beyond clinical factors. Patient-reported outcomes aid in surgical decision-making, highlighting personalized burden understanding and potential benefits of using quality of life measures in preoperative settings.

Journal Article by Ueland TE, Horst SN (…) Hawkins AT et 5 al. in J Gastrointest Surg

Copyright © 2024 Society for Surgery of the Alimentary Tract. Published by Elsevier Inc. All rights reserved.

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Genetic Background Influence on Weight Loss After Bariatric Surgery

Individuals with lower polygenic risk scores experienced better weight loss outcomes after bariatric surgery compared to those with higher scores, especially in patients undergoing roux-en-y gastric bypass. Genetic background, assessed through polygenic risk scores, plays a significant role in long-term weight loss post-surgery, alongside factors like sex, age, and initial BMI. These findings suggest the potential of utilizing genetic risk scores to predict bariatric surgery outcomes.

Journal Article by Peña E, Mas-Bermejo P (…) Rosa A et 6 al. in J Gastrointest Surg

Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.

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Improved Survival with CRS + HIPEC in HCC-PM Patients

CRS + HIPEC provides significant benefits to HCC-PM patients, with 89.0% 1-year and 3-year OS rates. Some patients achieved prolonged PFS, enhancing treatment options for this challenging condition. Incorporating CRS + HIPEC into the treatment regimen is a strategic therapeutic choice for HCC-PM patients, supported by the study’s findings of extended survival outcomes.

Journal Article by Yan G, Zhang K, Yan L and Zhang Y in World J Surg Oncol

© 2024. The Author(s).

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Predicting Biliary Complications in Liver Transplant Patients

Utilizing LASSO logistic regression, researchers identified key risk factors for biliary complications in end-stage hepatic alveolar echinococcosis patients post ex vivo liver resection and autotransplantation. A prognostic nomogram model incorporating age, bile duct dilation, portal hypertension, and resection segments showed good discrimination and accuracy. The model predicted biliary complications with an AUC of 0.818 and a predictive range of 9% to 85% for clinical benefit.

Journal Article by Lin X, Shao YM, Zhang RQ and Aji T in Eur J Med Res

© 2024. The Author(s).

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Comparison of Malnutrition Screening Tools in Hospitalized Patients

Prompt identification of malnutrition among hospitalized patients is crucial. A study compared 5 screening tools based on GLIM criteria on 1,397 inpatients. Results showed GMS had highest sensitivity (87.40%) and NRS-2002, highest specificity (91.70%). MST aligned well with GLIM, emphasizing early diagnosis importance. Effective screening tools can improve treatment efficacy.

Journal Article by Arslan S, Dal N (…) Atan RM et 2 al. in Postgrad Med

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Preoperative ICG-R15 Testing Predicts Post-hepatectomy Liver Failure

Preoperative ICG-R15 testing effectively predicts post-hepatectomy liver failure (PHLF) following major liver resection. A retrospective review of 72 patients revealed that 38.9% experienced PHLF, with 33.3% being severity score B and 4.16% score C. Univariate and multivariate analyses identified future liver remnant, ICG-R15 levels, and blood transfusion as independent predictors of PHLF. These findings emphasize the value of preoperative ICG-R15 testing in assessing the risk of PHLF post major liver resection.

Journal Article by Sampath S, Patkar S (…) Goel M et 5 al. in Indian J Surg Oncol

© The Author(s), under exclusive licence to Indian Association of Surgical Oncology 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Pathologic Complete Response and Survival Paradox in Locally Advanced Rectal Cancer

Pathologic complete response (PCR) after preoperative chemoradiation correlates with improved overall survival for locally advanced rectal cancer patients. While total neoadjuvant therapy (TNT) increases PCR rates, it does not improve overall survival. Patients achieving PCR after TNT have worse survival compared to those with chemoradiation alone. The route to achieving PCR may be a crucial factor in predicting oncologic outcomes, challenging the notion that PCR uniformly signifies better prognosis.

Journal Article by Goffredo P, Suraju MO (…) Hassan I et 5 al. in Ann Surg Oncol

© 2024. Society of Surgical Oncology.

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Impact of Fat Embolism on Trauma Patients

Study reveals fat embolism in trauma patients associated with higher mortality, complications, and costs. Fat embolism linked to younger age, higher healthcare resource utilization. Trends show rising mortality and hospitalization costs over time in fat embolism group. Early identification crucial to improve outcomes and resource allocation for trauma patients.

Journal Article by Ali K, Cho NY (…) Benharash P et 5 al. in BMC Surg

Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.

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Sleeve Gastrectomy Promotes Type 2 Diabetes Remission

Significant weight loss and remission of type 2 diabetes mellitus were observed in patients post-sleeve gastrectomy. Patients exhibited low citrulline and high I-FABP levels preoperatively, which normalized postoperatively. The study found a positive correlation between the I-FABP/citrulline ratio and weight, BMI, glucose, insulin, and c-peptide levels. Sleeve gastrectomy not only improves enteroendocrine function but also aids in diabetes remission and counteracting obesity-related effects on the enteroendocrine system.

Journal Article by Aydin MA, Aykal G (…) Guler M et 4 al. in Am J Surg

Copyright © 2024 Elsevier Inc. All rights reserved.

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Intraoperative Hemodynamic Monitoring for Pancreatectomy

Advanced intraoperative hemodynamic monitoring combined with a clinical decision-making algorithm improved hemodynamic parameters during pancreatectomy, showing a 33.3% reduction in intraoperative hypotension, 31.6% increase in cardiac index, and 37.6% increase in stroke volume variation. Further investigation in larger studies is warranted to validate these findings.

Journal Article by Galouzis N, Khawam M (…) Dull RO et 6 al. in J Surg Res

Copyright © 2024 Elsevier Inc. All rights reserved.

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