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3D Laparoscopy Shows Superior Therapeutic Effects in Colorectal Cancer Treatment

3D laparoscopy demonstrates significant improvement in intraoperative blood loss, faster postoperative recovery, shorter operation time, and hospital stay compared to conventional 2D laparoscopy for radical rectal cancer surgery. However, no clear advantage was observed for radical colon cancer surgery. Additionally, 3D laparoscopy increases the number of dissected lymph nodes in radical colon cancer cases but not in rectal cancer cases, suggesting its potential for enhancing therapeutic outcomes in colorectal cancer treatment.

Review by Zhan S, Zhu Z (…) Wan Z et 5 al. in Am Surg

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Robotic complex hepatectomy reduces perioperative morbidity for hepatocellular carcinoma

Robotic complex hepatectomy (RCH) offers advantages over laparoscopic complex hepatectomy (LCH) for patients with solitary hepatocellular carcinoma, showing lower blood loss, transfusion rates, and postoperative complications, including 30-day morbidity and post-hepatectomy liver failure. Additionally, RCH is an independent protective factor for reducing major morbidity. These findings suggest that RCH may be a preferable choice for patients requiring complex hepatectomy, due to its ability to minimize postoperative morbidity.

Journal Article by Huang XK, Lu WF (…) Zhang CW et 16 al. in HPB (Oxford)

Copyright © 2024 International Hepato-Pancreato-Biliary Association Inc. Published by Elsevier Ltd. All rights reserved.

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Effective Total Neoadjuvant Therapy Protocols for Locally Advanced Rectal Cancer

Long-course chemoradiotherapy with consolidation chemotherapy, short-course radiotherapy with consolidation chemotherapy, and induction chemotherapy with long-course chemoradiotherapy outperform standard treatment for locally advanced rectal cancer, improving pathological complete response rates. These findings support their recognition as first-line treatments, offering good tolerability and optimal postoperative outcomes.

Meta-Analysis by Turri G, Ostuzzi G (…) Pedrazzani C et 7 al. in JAMA Netw Open

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Improved Prediction Models for Recurrence in Unresectable HCC Patients

Novel nomograms utilizing multimodal imaging features and clinical data were developed and validated for predicting disease-free survival after TACE-based downstaging therapy followed by surgical resection in unresectable HCC patients. The nomograms outperformed five major staging systems in risk stratification, offering more accurate prognostic information to guide individualized treatment strategies for patients at high risk of postoperative recurrence.

Journal Article by Zuo M, Jiang H (…) An C et 3 al. in Int J Surg

Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.

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Distinct Tertiary Lymphoid Patterns in Colorectal Cancer

Deciphering heterogeneous tertiary lymphoid structures (TLS) patterns in colorectal cancer revealed three clusters with different prognostic implications. High metabolic activity and stromal pathways linked to worse outcomes, while immune activation pathways indicated improved prognosis and better response to immunotherapy. A new TLScore based on 9 core genes showed potential for guiding treatment decisions, highlighting the promise of personalized medicine in colorectal cancer.

Journal Article by Lei JX, Wang R (…) Gao F et 8 al. in Int J Surg

Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.

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Dependent functional status as a risk factor for 30-day mortality after colectomy

Dependent functional status significantly increases the risks of mortality, pulmonary complications, sepsis, extended postoperative NPO/NGT use, non-home discharge, 30-day readmission, and longer hospital stays post-colectomy for volvulus. Identifying DFS as an independent risk factor emphasizes its impact on postoperative outcomes, enabling tailored preoperative assessments and care strategies for these at-risk patients.

Journal Article by Li R in Clin Res Hepatol Gastroenterol

Copyright © 2024. Published by Elsevier Masson SAS.

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Bariatric Intervention Improves Steatohepatitis

Bariatric intervention significantly reduced BMI and intrahepatic fat in patients with obesity, leading to improvements in histologic features of metabolic dysfunction-associated steatohepatitis. Nonalcoholic fatty liver disease activity score decreased significantly at various time points post-intervention. These findings suggest that bariatric intervention may be an effective alternative for obese patients with metabolic dysfunction-associated steatohepatitis unresponsive to lifestyle changes or medical treatment.

Journal Article by Hwang J, Hwang H (…) Cho Y et 7 al. in Clin Mol Hepatol

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Decreasing Superficial and Deep Infections in Colorectal Surgery

A noticeable decline in rates of superficial and deep incisional infections has been observed from 2013 to 2020 in colorectal surgery, attributed to increased use of minimally invasive techniques. However, organ space infections have shown an upward trend during the same period. Adoption of minimally invasive approaches has significantly lowered the odds of surgical site infections. Further research is needed to refine infection prevention strategies and explore novel interventions for postoperative infections.

Journal Article by Chang J, Karlsdottir BR (…) Gribovskaja-Rupp I et 5 al. in Dis Colon Rectum

Copyright © The ASCRS 2024.

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Synoptic Operative Report for Rectal Prolapse

International expert consensus on operative descriptors for rectal prolapse surgery was achieved through a Delphi process. A synoptic operative report was developed, including 16 key descriptors with over 70% consensus. This standardized reporting aims to enhance clinical communication, quality measures, and research in pelvic floor disorders. The survey involved 176 surgeons across different regions, establishing a comprehensive framework for intraoperative variables. Video abstract available for further insight.

Journal Article by Olson CH, Bordeianou L (…) Gurland BH et 7 al. in Dis Colon Rectum

Copyright © The ASCRS 2024.

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Outcomes of Laparoscopic Revisional Sleeve Gastrectomy with Hiatal Hernia Repair

Analysis of revisional and conversional sleeve gastrectomy procedures with concurrent hiatal hernia repair showed increased operative time, risk of postoperative pneumonia, and readmission within thirty days for patients with hiatal hernia repair. Despite these findings, patients undergoing laparoscopic revisional or conversional sleeve gastrectomy with hiatal hernia repair did not experience higher risks of death, postoperative bleeding, leaks, or reoperations. Overall, complications were low, suggesting that hiatal hernia repair is a safe option in early postoperative care.

Journal Article by Perez SC, Ericksen F (…) Wheeler AA et 2 al. in Surg Endosc

© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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