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Parathyroid Precision: NIRAF Overlay Imaging Emerges as a Surgical Sidekick

In the quest for parathyroid precision, researchers unveil the potential of near-infrared autofluorescence (NIRAF) overlay imaging. 189 surgical contenders underwent the spotlight, revealing 543 parathyroid glands (PGs). Results? A tiebreaker, with surgeons and overlay imaging each spotting PGs in 111 cases. The NIRAF playbook dictates a sweet spot: 8-12 cm distance, a 90° angle, and an IR intensity of 34.5%. Conclusion: NIRAF overlay imaging proves a worthy sidekick in the parathyroid pursuit, enhancing intraoperative localization.

Journal Article by Arikan M, Hegazy J (…) Riss P et 4 al. in Ann Surg Oncol

© 2023. The Author(s).

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Neoadjuvant Chemotherapy Takes the Lead in Prolonging Survival for Esophageal Squamous Cell Carcinoma

In the realm of esophageal squamous cell carcinoma (ESCC), the battle between neoadjuvant chemotherapy (NAC) and adjuvant chemotherapy (AC) takes center stage. A squad of 684 ESCC patients engaged in this retrospective face-off at Henan Cancer Hospital. Post Propensity Score Matching (PSM), the NAC squad flexed its muscles, showcasing prolonged overall survival (OS) and disease-free survival (DFS), while reducing total and local recurrence rates. The study concludes: NAC plus surgery emerges as the victorious combo for clinical stage II and III ESCC patients.

Journal Article by Sun HB, Yan S (…) Sun HB et 9 al. in Ann Surg Oncol

© 2023. Society of Surgical Oncology.

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Navigating the Landscape of Endoscopic Weight Loss Therapies

As the battle against obesity rages on, clinicians explore the endoscopic arena for weight loss interventions. The review dissects diverse endoscopic bariatric therapies, from intragastric balloons to endoluminal procedures. While these methods exhibit short-term effectiveness, concerns linger about weight rebound. Adverse events, including nausea and vomiting, pepper the landscape. Despite the challenges, the endoscopic toolkit emerges as a compelling frontier in the quest for novel, safe, and straightforward obesity treatments.

Review by Abdulla M, Mohammed N and AlQamish J in World J Gastroenterol

©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.

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Rethinking Lateral Pelvic Node Metastasis in Advanced Rectal Cancer After Chemoradiotherapy

In the realm of advanced rectal cancer, the question of lateral pelvic node metastasis being regional or systemic sparks debate. A study dives in, revealing that after preoperative chemoradiotherapy, outcomes for lateral lymphatic metastasis mirror upward spread, challenging the Western perception of it as systemic. No survival disparities emerged between lateral node dissection and total mesorectal excision alone. The findings suggest lateral pelvic node metastasis might be more regional than previously thought, stirring the pot in rectal cancer treatment paradigms.

Journal Article by Kim HJ, Choi GS (…) Kim JG et 5 al. in Dis Colon Rectum

Copyright © The ASCRS 2023.

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Bariatric Surgery: A Defender Against Obesity-Associated Cancers

In the fight against obesity-related cancers, bariatric surgery emerges as a hero. A multi-center study reveals that adults with obesity undergoing bariatric surgery enjoy a significantly lower risk of developing new obesity-associated cancers compared to their nonsurgical counterparts. At the 10-year mark, the bariatric surgery group boasts a 4.0% incidence, while the nonsurgical group hits 8.9%. Breast, colon, liver, ovarian, and endometrial cancers all occur at lower rates in the bariatric surgery group, showcasing the procedure’s cancer-protective prowess.

Journal Article by Chittajallu V, Mansoor E (…) Simons-Linares R et 5 al. in Obes Surg

© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Comparing Laparoscopic and Open Approaches for Peptic Ulcer Perforation

This study scrutinizes laparoscopic versus open surgery for peptic ulcer perforation (PUP). Analyzing 29 studies (17,228 patients), laparoscopy emerges as a superior choice. Laparoscopic intervention correlates with shorter hospital stays, reduced blood loss, and fewer complications. Remarkably, laparoscopy also exhibits a lower mortality rate. However, it’s not without its complexities, showing a higher overall complication rate. In the realm of PUP repair, this study asserts laparoscopy as a commendable option, offering advantages, albeit with some nuances.

Journal Article by Li ZW, Tong Y (…) Peng D et 7 al. in Langenbecks Arch Surg

© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

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CRP: Early Indicator of Anastomotic Leakage After Esophageal Cancer Surgery

In the world of esophageal cancer surgery, a study from Karolinska University Hospital unveils CRP (C-reactive protein) as a superhero. Analyzing 612 patients, the research identifies a spike of ≥4.65% in CRP levels between postoperative days 2 to 3 as a signal for anastomotic leakage (AL) risk after esophagectomy. Those with CRP over 211 mg/L on day 2 face a 3.67-fold higher risk. Early CRP changes emerge as the early-warning beacon for detecting AL in the post-esophageal cancer surgery landscape.

Journal Article by Ri M, Tzortzakakis A (…) Nilsson M et 4 al. in Langenbecks Arch Surg

© 2023. The Author(s).

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CT Staging Quirks: Unpacking the Nuances in Advanced Colon Tumor Diagnosis

In the quest for accurate preoperative staging of advanced colon tumors, the CT scan takes the stage. However, the spotlight reveals some hiccups. A national retrospective study with 1950 patients unfolded the CT’s script, showing a 57% sensitivity in nailing T4 tumors, a 63% overall accuracy in N staging, and a 94.8% precision in sniffing out peritoneal metastases. The CT performance review suggests it still fumbles in the nuances of T4 staging, lymph nodes, and preoperative peritoneal metastasis detection.

Journal Article by García Del Álamo Hernández Y, Cano-Valderrama Ó (…) Collaborative Group For The Study Of Metachronous Peritoneal Metastases Of pT Colon Cancer None et 14 al. in J Clin Med

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Mapping the Road: Lymph Node Metastasis Spells Prognostic Challenge in Nonfunctioning Pancreatic Neuroendocrine Neoplasms

For those tackling nonfunctioning pancreatic neuroendocrine neoplasms (NFPanNENs), the question was: How much lymph node removal is the sweet spot? This study dug into 84 patients’ data, revealing that lymph node metastasis near the tumor was the key player in predicting a tough road ahead. Pancreatic head tumors saw trouble at stations 8, 13, and 17, while body and tail tumors faced issues at station 11. The verdict? Post-surgery, a nod to peri-pancreatic lymphadenectomy for NFPanNENs might be the move.

Journal Article by Shintakuya R, Uemura K (…) Takahashi S et 8 al. in J Clin Med

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Beyond Laparoscopy: Gravity’s Role in Optimal Patient Positioning for Endoscopic Procedures

In the world of surgery, positioning isn’t just a laparoscopy thing—endoscopic procedures need it too. This study dives into patient positioning’s impact on endoscopy. It’s not just about turning patients around; it’s about tilting surgical beds and considering gravity’s role. From lesion exposure to avoiding sample mishaps, gravity plays a crucial part. Surgeons, take note: patient anatomy and endoscope positioning matter in endoscopy, especially when there’s radiological backup.

Review by Polese L, Giugliano E and Valmasoni M in J Clin Med

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