A multicenter study developed and validated the prealbumin-bilirubin (preALBI) score as an alternative to the widely used albumin-bilirubin (ALBI) score for predicting long-term survival after hepatectomy for hepatocellular carcinoma (HCC). The preALBI score, incorporating serum prealbumin and bilirubin levels, showed superior performance in predicting survival compared to the ALBI score and Child-Pugh grade. Leveraging the […]
Category: HPB & Spleen
Liver Resection Techniques: Efficacy and Safety in Modulating Future Liver Remnant
In a systematic review and network meta-analysis of 23 studies comprising 1557 patients, lvd was found to achieve the greatest increase in flr, while alpps was most effective in preventing dropout before completion hepatectomy. Pvl tended to be associated with a longer time to completion hepatectomy, and liver failure occurred less frequently after lvd, compared […]
Nomogram Combined Treatment Data is More Effective than AJCC Staging System for Predicting Overall Survival in GEP-NETs
Researchers conducted a study to develop and validate a nomogram for predicting overall survival (OS) in patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs). Using data from the SEER registry, they identified key prognostic factors and compared the nomogram’s performance to the AJCC staging system. The results showed that the nomogram, which combined treatment data, had a […]
Three-Dimensional-Guided Laparoscopic Radical Resection for Left Perihilar Cholangiocarcinoma: Improved Precision and Efficiency
Utilizing three-dimensional reconstruction, clinicians performed a successful laparoscopic left hepatectomy and caudate lobectomy in a patient with left perihilar cholangiocarcinoma. The reconstruction revealed tumor invasion into the left hepatic artery and left portal vein. The procedure lasted 425 minutes with minimal blood loss. The patient’s postoperative recovery was smooth, and no recurrence was observed at […]
Pancreatectomy Induces Cancer-Promoting Neutrophil Extracellular Traps: Implications for Perioperative Management
Post-pancreatectomy, patients exhibit elevated cancer-promoting neutrophil extracellular traps (NETs), peaking on days 3 and 4, linked to changes in neutrophil biology. NET-inducing cytokines (IL-8, IL-6, G-CSF) increase postoperatively, with the robotic approach potentially reducing NETs compared to open surgery. Patients with pancreatic leaks show increased NET markers. The study suggests pancreatectomy induces cancer-promoting NET formation, […]
Beppu score helps stratify recurrence risk and guide selection of perioperative chemotherapy for colorectal liver metastases
Recurrence-risk stratification using the Beppu score can help clinicians estimate the postoperative disease-free survival for colorectal liver metastases. The study identified three risk groups based on the Beppu score: low, moderate, and high-risk. For each group, different treatment options were recommended: hepatectomy alone for low-risk, hepatectomy with adjuvant chemotherapy for moderate-risk, and hepatectomy with preoperative […]
Higher Rate of Recurrence with Hybrid Resection for Laterally Spreading Lesions of the Papilla
Hybrid resection (HR) for laterally spreading lesions of the papilla, involving hot snare papillectomy and cold snare resection, was compared to conventional hot snare resection (CR) in a study. HR was associated with a significantly higher recurrence rate of recurrent or residual adenoma (RRAs) compared to CR. The odds of recurrence were 3.6 times higher […]
Indocyanine Green Fluorescence Navigation Enables Laparoscopic Anatomic Bi-segmentectomy
The study demonstrates that laparoscopic anatomic bi-segmentectomy using Takasaki’s approach and indocyanine green fluorescence navigation is technically feasible and safe, serving as a valuable alternative to formal right hepatectomy in select cases. The report describes a successful case of a 58-year-old male with hepatitis B virus-related hepatocellular carcinoma (HCC), where the laparoscopic procedure resulted in […]
Optimal Surveillance Interval for Branch Duct Intraductal Papillary Mucinous Neoplasm of the Pancreas Depends on Cyst Size and Morphologic Changes
The optimal surveillance interval for branch duct intraductal papillary mucinous neoplasm (IPMN) of the pancreas depends on the size of the cyst and morphologic changes detected during the initial 6-month follow-up. Findings from a large-scale, international cohort study suggest that for patients with cysts smaller than 20 mm and no morphologic changes during a 5-year […]
Grade A Post-Hepatectomy Liver Failure: Mortality Similar, but Increased Morbidity Compared to No PHLF
A study analyzing hepatectomy outcomes identified grade A post-hepatectomy liver failure (PHLF) as a distinct entity. Although mortality rates were similar between patients with grade A PHLF and those without, the former exhibited notably inferior postoperative outcomes, including increased morbidity, reoperation, nonoperative intervention, longer hospital stays, and higher readmission rates. Journal Article by Vitello DJ, […]