Racial and socioeconomic disparities impact access to curative treatments for hepatocellular carcinoma (HCC). African-American and Hispanic patients had lower odds of receiving ablative therapy and surgical resection compared to whites, while disparities in liver transplantation varied. While trends improved for white and API/other patients, African-American and Hispanic patients showed non-significant changes over time, indicating widening […]

Infrahepatic inferior vena cava clamping combined with Pringle maneuver leads to greater reduction in central venous pressure, reduced intraoperative blood loss, and decreased blood transfusion during hepatectomy compared to Pringle maneuver alone. Patients in the combined technique group also experienced shorter hospital stays and lower overall complication rates without affecting operative times. This meta-analysis suggests […]

Metabolomics analysis identified indoleacetate, 3-hydroxydecanoate, and retention index as top candidate biomarkers for early detection of pancreatic cancer in plasma samples. A logistic regression model incorporating these metabolites, along with other clinical factors, significantly improved risk prediction compared to models without these markers. Continued research is needed to establish the clinical utility of these biomarkers […]

Pancreatic surgery outcomes: Snapshot study across 67 countries reveals significantly higher postoperative mortality rates in low-to-middle-HDI nations compared to high-HDI counterparts. Over two-thirds of patients experienced complications, with a 90-day mortality rate of 5.4%. Failure-to-rescue rates were notably higher in lower-HDI countries. Collaborative efforts among pancreatic surgeons globally are needed to address disparities and enhance […]

Study on 80,070 patients undergoing hepatic resection reveals a 1.46% occurrence of postoperative delirium, with key risk factors including older age, male sex, depression, and various comorbidities. Patients with delirium had longer hospital stays, higher costs, and increased mortality rates than those without. Understanding these factors is crucial for enhancing care management and outcomes in […]

Despite discouragement for hepatectomy in intermediate/advanced hepatocellular carcinoma, nomograms were developed and validated for predicting survival and recurrence. These nomograms, based on 10 and 6 independent variables, respectively, outperformed conventional staging systems. They accurately stratified risk and can assist clinicians in personalized surgical decisions, prognosis estimation, and anti-recurrence therapy strategies for patients with intermediate/advanced hepatocellular […]

Direct-acting antivirals significantly improve outcomes of liver resection for hepatitis C-related hepatocellular carcinoma. Patients achieving sustained virological response (svr) had significantly better survival rates compared to those who did not. Introduction of direct-acting antivirals in the post-era resulted in superior survival outcomes. Svr was identified as an independent predictor of survival. The study highlights the […]

Robotic liver resection (RLR) showcases longer operative times than laparoscopic liver resection (LLR) for hepatocellular carcinoma with no major disparities in other short-term outcomes. While overall survival remains alike, RLR promotes enhanced recurrence-free survival and a more proficient learning curve after the 11th case. RLR proves effective and safe, reducing recurrence rates significantly compared to […]

Delayed gastric emptying (DGE) after laparoscopic pancreaticoduodenectomy (LPD) was studied in 827 patients. Preoperative biliary drainage, blood loss, and major complications were significant risk factors for DGE. Higher BMI, soft pancreatic texture, and perioperative transfusion increased the risk of secondary DGE. Identifying at-risk patients can lead to early interventions and improved clinical decisions for shorter […]