Category: HPB & Spleen

Impact of 3D-Printed Models on Complications in Hepatobiliary Laparoscopic Surgery

3D-printed models reduce intraoperative blood loss and postoperative complications, particularly bile leakage, in complex hepatobiliary laparoscopic surgeries. Patients guided by 3D models had significantly lower comprehensive complication index scores compared to the control group. Multivariable analysis confirmed 3D models as independent protective factors against complications. Subgroup analysis emphasized the efficacy of 3D models in reducing […]

Comparative Analysis of Liver Resection for Non-B Non-C and Virus-Associated Hepatocellular Carcinoma

Increasing cases of non-hepatitis B and non-hepatitis C hepatocellular carcinoma (NBNC-HCC) prompt a comparison with hepatitis virus-associated HCC. A retrospective study of 1321 liver resections showed comparable operative outcomes and long-term survival between matched NBNC-HCC and HV-HCC groups. Independent prognostic factors for overall survival were identified, with NBNC-HCC cases reaching up to 70% of total […]

Outcome of Laparoscopic Hepatectomy in Precision Surgery

During a study of 1056 patients undergoing laparoscopic hepatectomy, 75% achieved a textbook outcome (TO). Factors like age, ASA classification, and tumor characteristics influenced TO attainment. Notably, patients reaching TO showed improved survival rates, suggesting its importance in precision surgery and patient outcomes. Journal Article by Xu Z, Lv Y (…) Zhu C et 8 […]

Enhanced Disease-Free Survival in Pancreatic Cancer Patients with Neoadjuvant Chemotherapy and Vascular Resection

Neoadjuvant chemotherapy before pancreaticoduodenectomy with vascular resection led to improved disease-free survival in pancreatic cancer patients. Patients who received neoadjuvant chemotherapy had more favorable pathological outcomes, decreased vascular invasion, and completed chemotherapy more often. The neoadjuvant chemotherapy group exhibited a significant increase in disease-free survival compared to those who underwent upfront surgery, highlighting the advantages […]

Impact of Postoperative Complications on Prognosis in Patients with Hepatocellular Carcinoma

Postoperative complications significantly impact patient outcomes in hepatocellular carcinoma. Patients with moderate/severe complications had worse recurrence-free survival compared to those with no/mild complications. Notably, low and medium alpha-feto protein-tumor burden score patients with complications had higher recurrence risks, whereas complications did not affect high score patients. These findings highlight the importance of reducing postoperative complications […]

Comparing Local and Remote Ischemic Preconditioning in Hepatectomy

Local ischemic preconditioning (LIPC) and remote ischemic preconditioning (RIPC) were found to be superior to no-preconditioning in reducing postoperative serum transaminase levels in hepatectomy. There was no significant difference between the two methods in postoperative liver function and surgical outcomes. RIPC showed potential benefits in improving liver function, particularly in patients with cirrhosis or those […]

Comparing Liver Transplant and Liver Resection for Multifocal Hepatocellular Carcinoma

Liver transplant (LT) was associated with improved long-term survival compared to liver resection (LR) in patients with multifocal hepatocellular carcinoma (MHCC). Factors such as race, insurance status, and treatment facility influenced the likelihood of receiving LT. This study highlights the clinical and sociodemographic disparities between LT and LR patients, emphasizing the lower mortality risk associated […]

Analysis of Learning Curve in Robotic Hepatectomies

Analysis of 500 robotic hepatectomies revealed significant number of cases needed to achieve mastery in minor, major, and technically challenging resections. Surgeons can utilize this data to enhance patient safety and outcomes, providing valuable insights for those gaining experience in robotic hepatectomies. The findings highlight the importance of overcoming specific learning curves to achieve long-term […]

Improved Recurrence Surveillance with Personalized Circulating Tumor DNA Monitoring

Personalized circulating tumor DNA monitoring using a tumor-informed assay significantly improves recurrence surveillance and management in patients with colorectal liver metastases. Detectable ctDNA at specific time points post-surgery is associated with higher recurrence risk, serving as an independent prognostic marker. Longitudinal ctDNA analysis accurately predicts relapse, leading to increased secondary resection rates and improved outcomes. […]