Combining sequential hepatic vein embolization with portal vein embolization significantly boosts liver volume and function before major hepatectomy. Future remnant liver volume regeneration improved to 35.5% with sequential embolization, versus 26.2% with portal vein embolization alone. Both procedures had no severe complications, indicating safety in surgical applications. Surgeons should consider sequential embolization to optimize outcomes […]
Category: HPB & Spleen
Effective Antibiotic Strategy Cuts Perineal Wound Infections in APR
A 4-day course of sulbactam/ampicillin effectively lowers perineal wound infections after abdominoperineal resection for rectal cancer. Incidence of perineal wound infection dropped significantly from 46% with cefmetazole to 14% with sulbactam/ampicillin. This multicenter trial involved 80 patients, with a focus on surgical site infections and overall complications. Consider shifting to a 4-day sulbactam/ampicillin regimen to […]
Advances in Pancreatic Cancer Surgery Enhance Patient Outcomes
Surgical management of pancreatic cancer has improved, leading to better patient outcomes and survival rates. Five-year survival rates for pancreatic ductal adenocarcinoma have risen from under 5% to about 13%. Enhanced perioperative management and new scoring systems have reduced postoperative mortality. Centralizing care in dedicated pancreas units is crucial for optimal treatment, particularly for complex […]
Laparoscopic Access Reduces Risks in Right Lobe Liver Tumor Surgery
Laparoscopic retroperitoneal partial hepatectomy offers a safer approach for deep right lobe liver tumors. Complete success in 72 patients; conversion to open surgery in 10 cases. Mean operative time of 140 minutes, with only 150 ml blood loss; average hospital stay was 8.3 days. This technique leads to faster recoveries with fewer complications, making it […]
Neoadjuvant Therapy Duration Impacts Pancreatic Cancer Surgery
Shorter neoadjuvant therapy (≤8 weeks) boosts surgical success in pancreatic cancer. Surgical resection rate significantly higher with ≤8 weeks (66.7%) versus >8 weeks (33.5%). This trend holds for both resectable (73.9% vs 44.7%) and borderline resectable cases (66.4% vs 22.5%). Longer therapy does not improve resection margins or survival, suggesting risks in delaying surgery. No […]
Cryoablation Shows Promise for Locally Advanced Pancreatic Cancer
Cryoablation is a safe and effective treatment for locally advanced pancreatic cancer (LAPC), enhancing patient outcomes when surgery isn’t feasible. No perioperative deaths; smooth surgeries across all patients. Postoperative pancreatic fistulas occurred in 75% of cases, but most were manageable. This technique can prolong survival and improve quality of life by addressing tumor progression directly. […]
Improved Prediction of Lymph Node Metastasis in Pancreatic Cancer
Integrating the neutrophil-albumin ratio with multi-phase CT enhances lymph node metastasis detection in pancreatic cancer patients. A model combining a neutrophil-albumin ratio greater than 0.13 and certain CT findings accurately identifies patients at high risk for lymph node metastasis before surgery. Among 129 patients studied, factors like tumor size and hemangioma thrombosis also showed significant […]
Guidance for Better Liver Surgery Care
New European consensus offers critical updates on liver resection management. Strong recommendations include prehabilitation and early mobilization. Evidence gaps identified in perioperative thromboprophylaxis and post-hepatectomy liver failure management. Standardizing practices and expanding multicenter studies are essential to enhance surgical outcomes. Only 32 statements reached consensus from over 200 publications, revealing variability in evidence strength. Consensus […]
Minimally invasive surgery reduces loss of independence after pancreatoduodenectomy in the elderly.
22 patients (16.7%) over 65 experienced loss of independence after surgery, compared to none under 65. Key risk factors include age ≥80 years, sarcopenia, and open surgical approach. Identifying these factors can enhance patient selection and surgical decision-making. A loss of independence score was developed, showing a strong correlation with the incidence of loss of […]
Fluid Management Revolution in Pancreaticoduodenectomy
Fluid management impacts outcomes in pancreaticoduodenectomy for localized cancer. Excessive fluid can lead to complications like postoperative pancreatic fistula and increased inflammatory responses. A shift towards restrictive fluid regimens has shown to reduce overall complications and shorten hospital stays. Goal-directed fluid therapy (GDFT) tailors fluid delivery, improving outcomes but requires careful balance to avoid hypoperfusion. […]
