Patients with very early intrahepatic cholangiocarcinoma (ICC) show significant long-term survival, with 1-, 3-, and 5-year overall survival rates at 92.3%, 72.6%, and 58.0%, respectively. However, elevated carbohydrate antigen 19-9 (CA19-9) levels correlate with worse overall and recurrence-free survival rates, indicating more aggressive tumor features. Such biomarkers could refine perioperative treatment strategies and identify patients […]
Category: HPB & Spleen
Surgical Resection After Systemic Therapy Shows Promising Outcomes in Liver Cancer
Surgical resection post-systemic therapy for hepatocellular carcinoma (HCC) yields encouraging long-term outcomes. In a cohort of 96 patients, median overall survival reached four years, with one-year survival rates at 86.1%. R0/R1 resection correlated with improved progression-free and overall survival, presenting a significant therapeutic advantage. Complications were manageable, with no 30-day mortalities and a 4.2% rate […]
Laparoscopic Ultrasound Resection Enhances Survival in Colorectal Liver Metastases
Laparoscopic ultrasound-guided resection and microwave ablation significantly improve patient outcomes for colorectal liver metastases (CRLM). In a study of 300 patients, the technique effectively reduced complications and enhanced survival when compared to traditional imaging methods. Notably, intraoperative contrast-enhanced ultrasound with Sonazoid emerged as an independent prognostic factor, underlining its clinical relevance in surgical oncology. This […]
Interventional Endoscopy Revolutionizes Treatment for Complex Gastroenterological Issues
Endoscopic ultrasonography (EUS) has transformed from a diagnostic tool to a crucial therapeutic method. Today, EUS-guided procedures are standard for managing symptomatic pancreatic fluid collections and offer alternatives for high-risk surgical patients with acute cholecystitis. It also provides solutions for biliary obstructions after failed ERCP. New techniques, including transgastric ERCP and gastrojejunostomy, tackle issues stemming […]
Early Exercise Speeds Recovery for Pancreatic Cancer Surgery Patients
Early progressive resistance exercise after pancreaticoduodenectomy accelerates recovery, significantly reducing time to first water intake, food intake, ambulation, and length of hospital stay. With 80 patients involved, those engaging in structured exercise reported faster functional recovery compared to controls receiving standard care. The findings highlight the need for integrating exercise protocols into postoperative care to […]
New MRI Scoring Model Accurately Predicts Early HCC Recurrence Post-Surgery
A novel MRI-based scoring model effectively predicts early recurrence of hepatocellular carcinoma (HCC) after surgical resection. Analyzing data from 310 patients, researchers identified tumor number, tumor margin, peritumoral enhancement, and macrovascular invasion as key predictors. With a simple scoring system, the model demonstrated high sensitivity (83.9%) and specificity (77.8%), offering a reliable tool for tailoring […]
Same-day pancreatic clinics nearly double survival for metastatic patients
Same-day pancreatic multidisciplinary clinics (PMDC) significantly enhance care for metastatic pancreatic cancer patients. This approach increases rates of genetic testing, access to palliative services, and timely treatment initiation. Notably, PMDC patients survived an average of 487 days compared to 267 days for those receiving standard care. Improved enrollment in clinical trials further highlights PMDC’s role […]
New Non-Water-Cooled Microwave Ablation Needle Minimizes Carbonization Risks
A groundbreaking non-water-cooled microwave ablation needle with a double-layer vacuum design significantly reduces carbonization while maintaining ablation efficacy. Experimental results reveal that a long-needle variant forms a carbonization-free solidification zone of 34 mm in 180 seconds, outperforming its short-needle counterpart, which takes 300 seconds for a 30 mm zone. This innovation ensures larger, spherical coagulation […]
Preoperative Biliary Drainage Cuts Mortality Risk in High Bilirubin Patients
In patients undergoing pancreaticoduodenectomy with severe hyperbilirubinemia (≥14.6 mg/dl), preoperative biliary drainage significantly reduces 90-day mortality from 13.3% to lower rates seen in other groups (2.9-5.7%). While biliary drainage increases the risk of surgical site infections (21.2-26.4%), it decreases overall morbidity compared to non-drained patients who face higher rates of acute respiratory distress syndrome (6.0%) […]
Braun Enteroenterostomy Reduces Severe Delayed Gastric Emptying After Pancreaticoduodenectomy
Implementing Braun enteroenterostomy (BEE) in pancreaticoduodenectomy significantly lowers the incidence of severe delayed gastric emptying (DGE) and major complications, enhancing patient outcomes. In a study of 214 patients, those receiving BEE experienced a drastic reduction in severe DGE (2.6% vs. 15.9%) and shorter hospital stays (14.7 days vs. 21.4 days). With a 56% reduction in […]