Experts from the European Society of Endocrine Surgeons provide evidence-based recommendations for surgery in advanced small bowel neuroendocrine tumours, addressing key controversial topics such as primary tumour resection, cytoreduction, lymph node clearance, and management of unknown primary tumours. The recommendations, based on a systematic literature review of 84 papers due to lack of randomized controlled […]
Category: Intestine and Lower Gastrointestinal Tract
Effectiveness of Kono-S Anastomosis in Reducing Recurrence in Crohn’s Disease
A nationwide study with 433 patients undergoing ileocolonic resection, including 155 with Kono-S anastomosis, found no significant reduction in endoscopic recurrence compared to conventional side-to-side anastomosis. In a 1:2 propensity score-matched comparison, endoscopic recurrence (≥i2) occurred in 47.5% of patients with Kono-S and 44.3% with conventional anastomosis, showing no statistically significant difference (p = 0.6745). […]
Optimal Parameters for Tissue Welding in Small Bowel Anastomosis
High-frequency electric welding technology for intestinal end-to-end anastomosis shows promise. In vitro and in vivo experiments revealed that a compression pressure of 250 kpa, voltage of 60 V, and 15-second duration resulted in the highest anastomotic strength with minimal thermal damage. Experimental pigs showed no adverse reactions, achieving a 100% survival rate. This technology could […]
High Rate of Emergency Surgery for Sigmoid Diverticulitis in France
This study from 41 French hospitals reveals a 33% rate of emergency surgery for sigmoid diverticulitis, significantly associated with patient age, BMI
Surgery improves quality of life in patients with recurrent diverticulitis
This systematic review and meta-analysis suggest that surgery for recurrent diverticulitis may enhance long-term quality of life compared to conservative treatment. Although associated with risks, surgical intervention resulted in higher SF-36 and GIQLI scores and fewer recurrences. These findings advocate for considering surgery in patients with ongoing or recurrent diverticulitis to potentially alleviate symptoms and […]
Impact of Hazard Function Analysis on Prognosis After Colorectal Cancer Recurrence
Hazard function analysis provided new insights into patient prognosis post colorectal cancer recurrence, revealing a peak risk of death at 2.9 years post-recurrence. Factors like metastatic organs, treatment type, and recurrence interval influenced short-term survival. The method offers an alternative to mean survival time and helps predict mortality risk changes over time. Journal Article by […]
Comparing Circular Staplers for Colorectal Anastomosis
A systematic review and meta-analysis compared two-row, three-row, and powered circular staplers for colorectal anastomosis. Powered staplers showed significantly lower risk of leakage and anastomotic bleeding, while three-row staplers only reduced leakage risk. Subgroup analysis did not reveal significant differences between the groups. An important finding was the superior risk reduction in leakage with powered […]
Disappointing Results of SMART Technique for Parastomal Hernia Repair
The study assesses the Modified Stapled Mesh Stoma Reinforcement Technique (mSMART) for parastomal hernia repair, revealing a high recurrence rate of 57.1% during follow-up. Despite low rates of surgical site occurrence and infection, disappointing outcomes indicate the need for alternative approaches in addressing parastomal hernias to improve patient outcomes and reduce recurrence. Journal Article by […]
Feasibility and Safety of Hepatic Arterial Infusion Pump Chemotherapy for Colorectal Liver Metastases
Feasible and safe, hepatic arterial infusion pump chemotherapy combined with systemic chemotherapy (HAIP-SYS) for colorectal liver metastases (CRLMs) showed promising results in a phase II study in the Netherlands. With a completion rate of 90% for two cycles, it demonstrated favorable disease control rates at first radiological evaluation and six months post-treatment. Although some patients […]
Laparoscopic Liver Resection Shows Comparable Outcomes to Open Liver Resection for High Tumour Burden Colorectal Liver Metastases
Laparoscopic liver resection (LLR) matches open liver resection (OLR) in outcomes for ≥ 3 colorectal liver metastases (CRLM), showing similar morbidity, mortality, and survival rates. LLR offers shorter hospital stays, advocating its consideration for selected patients with high tumour burden disease. This study, analyzing 277 patients, demonstrates comparable major hepatectomy rates between LLR and OLR. Although OLR […]