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Effectiveness of Near-Infrared Indocyanine Green Imaging in Laparoscopic Rectal Cancer Surgery

Utilizing the NIR-ICG imaging system during laparoscopic rectal cancer surgery can potentially reduce the incidence of anastomotic leakage (AL), a serious complication. The study protocol, a randomized controlled trial, aims to evaluate AL rates in patients receiving NIR-ICG during total mesorectal excision compared to conventional surgery. Expected outcomes and sample sizes have been carefully considered, with significance for future surgical practices and patient outcomes.

Clinical Trial Protocol by Sun L, Gao J (…) Zhang Z et 5 al. in BMJ Open

© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

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Enhanced Disease-Free Survival in Pancreatic Cancer Patients with Neoadjuvant Chemotherapy and Vascular Resection

Neoadjuvant chemotherapy before pancreaticoduodenectomy with vascular resection led to improved disease-free survival in pancreatic cancer patients. Patients who received neoadjuvant chemotherapy had more favorable pathological outcomes, decreased vascular invasion, and completed chemotherapy more often. The neoadjuvant chemotherapy group exhibited a significant increase in disease-free survival compared to those who underwent upfront surgery, highlighting the advantages of neoadjuvant therapy in this patient population.

Journal Article by Dillon DL, Park JY (…) Girgis MD et 5 al. in J Surg Oncol

© 2024 Wiley Periodicals LLC.

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Impact of Tumor Marker Regression Load Score on Prognosis of Gastric Cancer Patients

Novel findings suggest that the Tumor Marker Regression Load Score (TMRLS) is a significant independent prognostic factor for gastric cancer patients undergoing neoadjuvant chemotherapy and radical surgery. Patients with high TMRLS who received postoperative adjuvant chemotherapy showed better survival outcomes. The TMRLS-based nomogram demonstrated superior predictive performance compared to traditional staging methods. These results provide valuable insights for optimizing treatment strategies and improving long-term outcomes in gastric cancer patients.

Journal Article by Zhang LK, Zheng HL (…) Xie JW et 8 al. in Eur J Surg Oncol

© 2024 Elsevier Ltd, BASO ∼ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

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Impact of Disease Phenotype and Biologic Therapy on Re-resection Rates in Crohn’s Disease

Re-resection rates in Crohn’s disease patients are significantly influenced by disease activity and stoma reversals. The study reveals that early initiation of biologic therapy after primary resection can reduce the risk of re-resection for specific disease phenotypes. Factors such as disease location, behavior, smoking, and perianal disease also play a role in re-resection. These findings emphasize the potential of biologic therapy as a disease-modifying strategy for certain patient subgroups.

Journal Article by Poulsen A, Rasmussen J (…) Seidelin JB et 17 al. in J Crohns Colitis

© The Author(s) 2024. Published by Oxford University Press on behalf of European Crohn’s and Colitis Organisation. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.

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Impact of Postoperative Complications on Prognosis in Patients with Hepatocellular Carcinoma

Postoperative complications significantly impact patient outcomes in hepatocellular carcinoma. Patients with moderate/severe complications had worse recurrence-free survival compared to those with no/mild complications. Notably, low and medium alpha-feto protein-tumor burden score patients with complications had higher recurrence risks, whereas complications did not affect high score patients. These findings highlight the importance of reducing postoperative complications to improve prognosis, especially in patients with favorable tumor characteristics.

Journal Article by Endo Y, Tsilimigras DI (…) Pawlik TM et 18 al. in HPB (Oxford)

Copyright © 2024 International Hepato-Pancreato-Biliary Association Inc. Published by Elsevier Ltd. All rights reserved.

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Long-term Outcomes of Primary Closure in Pilonidal Sinus Disease

Comparing two surgical techniques for pilonidal sinus disease, midline closure without skin sutures showed significant advantages over excision and primary closure. Patients in the midline closure group experienced shorter surgical procedures, hospital stays, and time to return to work. Additionally, they had lower complication rates and no recurrence during a five-year follow-up period. This technique may be ideal for patients with midline sinus orifices.

Multicenter Study by Tas H and Karahan F in An Sist Sanit Navar

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Assessment of Rule-Based Guidelines for Postoperative Opioid Prescribing

Rule-based guidelines derived from in-hospital opioid consumption were compared to traditional methods for postoperative prescribing. Results show that rule-based guidelines tailored to individual patient needs outperformed fixed quantity approaches, leading to more accurate opioid prescribing. This study highlights the efficacy of personalized opioid prescribing based on in-hospital consumption, offering a simple yet effective method to prevent overprescribing and improve patient outcomes.

Journal Article by Beaulieu-Jones BR, Berrigan MT (…) Brat GA et 4 al. in J Am Coll Surg

Copyright © 2024 by the American College of Surgeons. Published by Wolters Kluwer Health, Inc. All rights reserved.

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Incidence of Morbidity and Mortality in Anti-reflux and Hiatal Hernia Surgery

This study reports historic morbidity and mortality rates in anti-reflux and hiatal hernia surgery, showing a 30-day morbidity rate of 18.2% and mortality rate of 0.2%, with most complications being minor. The 31-90-day period shows decreased rates. These findings suggest that while the surgeries have rare mortality, some patients may experience major complications, emphasizing the importance of informed patient consent and careful post-operative management.

Journal Article by Ivy ML, Baison G (…) Louie BE et 6 al. in J Am Coll Surg

Copyright © 2024 by the American College of Surgeons. Published by Wolters Kluwer Health, Inc. All rights reserved.

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Relaparoscopy for Severe Complications in Laparoscopic Colorectal Surgery

Relaparoscopy, guided by a standardized interdisciplinary protocol, demonstrates efficacy in managing major complications after laparoscopic colorectal surgery, leading to reduced treatment failure rates, including lower 90-day mortality and need for further surgery. Relaparoscopy, particularly in cases of anastomotic leak, correlates with shortened hospital stays, decreased postoperative morbidity, and less intensive postoperative care, indicating its potential in preserving the benefits of minimally invasive colorectal surgery.

Journal Article by Puccetti F, Vallorani A (…) Elmore U et 4 al. in World J Surg

© 2024 The Authors. World Journal of Surgery published by John Wiley & Sons Ltd on behalf of International Society of Surgery/Société Internationale de Chirurgie (ISS/SIC).

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Effectiveness of Virtual Care in a Multidisciplinary Bariatric Program

Transition to virtual care in a bariatric program saw significant increase in virtual visits, with high patient satisfaction rates. Patient preferences varied by healthcare providers, with most patients preferring in-person visits with medical doctors. Despite the preference, virtual care offers added benefits and high satisfaction rates. The study highlights the importance of a hybrid model to optimize healthcare resource distribution in multidisciplinary bariatric care.

Journal Article by Miamen L, Mathur V (…) Sheu E et 9 al. in Obes Surg

© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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