Machine learning models demonstrated significantly higher discriminatory performance compared to logistic regression models in predicting postoperative outcomes for patients undergoing gastrointestinal surgery. Standardized protocols and practical implementation of machine learning models should be further explored.
Review by Wang J, Tozzi F (…) Rashidian N et 12 al. in J Gastrointest Surg
Copyright © 2024 Society for Surgery of the Alimentary Tract. All rights reserved.
Adjuvant chemotherapy significantly increases long-term survival rates in patients with residual esophageal squamous cell carcinoma after neoadjuvant chemotherapy and surgery. Pathological lymph node status and adjuvant therapy were identified as independent prognostic factors. Adjuvant chemotherapy is especially beneficial for patients with nodal metastases.
Journal Article by Lu H, Liu JF (…) Wang Y et 2 al. in J Gastrointest Surg
Copyright © 2024. Published by Elsevier Inc.
QoL is maintained, with high symptom burden, during neoadjuvant therapy for gastrointestinal cancers. Functional well-being scores were consistently lower, while social well-being scores were higher. Common symptoms included fatigue, insomnia, and anxiety. Patients emphasized anxiety, fear, and frustration in free-text journaling but highlighted the importance of social support and confidence in healthcare providers.
Journal Article by Shannon AH, Sarna A (…) Cloyd JM et 9 al. in Ann Surg
Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
Robotic gastrectomy shows comparable 3-year disease-free survival and overall survival rates to laparoscopic gastrectomy in patients with gastric cancer. Sensitivity analysis also demonstrates similar outcomes in advanced cases. Robotic gastrectomy is associated with less blood loss, lower conversion rate, and shorter hospital stays, making it a safe approach for resectable gastric cancer cases.
Journal Article by Lu J, Li TY (…) Huang CM et 16 al. in Ann Surg
Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.
Minimum CA19-9 decrease of ≥40% and optimal decrease of ≥60% after induction chemotherapy are independent predictors for prolonged overall survival in patients with locally advanced pancreatic cancer, particularly when CA19-9 levels are elevated at baseline. These thresholds can guide treatment decisions during early response evaluation.
Journal Article by Seelen LWF, Doppenberg D (…) Besselink MG et 25 al. in Ann Surg
Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
This study establishes prioritized lists of operative procedures for simulation-based assessments in general surgery training, essential for competency-based programs. Through a Delphi consensus study, 21 and 16 procedures were identified as suitable for assessments at key training stages, aiding in trainee progression and end-of-training certification. This approach provides a structured method for content generation, enhancing the development of operative skill assessments for high-stakes scenarios.
Journal Article by Toale C, Morris M (…) Kavanagh DO et 4 al. in Ann Surg
Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
Older adults undergoing major elective surgery experience significant challenges with postoperative symptoms affecting their valued activities and well-being. Participants felt unprepared for the intensity and duration of symptoms, highlighting the need for support and education. Postoperative pain, gastrointestinal discomfort, and anxiety/stress were prominent issues. Assessing and addressing symptom burden could enhance quality of life and aid in meaningful recovery.
Journal Article by Keny C, Dillon EC (…) Tang V et 3 al. in Ann Surg
Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
Factors such as information-sharing practices, planning, and strong leadership support were associated with successful implementation of enhanced recovery pathways in hospitals. However, barriers such as pathway complexity and infrastructure posed challenges. Clinicians’ positive beliefs and knowledge about pathways were key to achieving greater adherence to process measures over time.
Journal Article by Yuan CT, Wu J (…) Rosen MA et 5 al. in Ann Surg
Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
Patients with high output chyle leaks post-esophagectomy benefited from early intervention, showing improved overall survival and shorter hospital stays. Non-operative and late interventional management were associated with increased mortality compared to prompt intervention. Early intervention reversed prognostic implications and led to outcomes similar to patients without chyle leaks.
Journal Article by Deboever N, Correa AM (…) Hofstetter WL et 11 al. in Ann Surg
Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.
A study comparing costs for 2 days vs. 5 days of postoperative antibiotics after appendectomy for complex appendicitis found that two days resulted in a statistically significant cost reduction. The difference in overall societal costs was – €625 in favor of the 2-day group, largely due to reduced hospital stay. Restricting postoperative antibiotics to 2 days was also found to be cost-effective, with estimated significant cost savings.
Journal Article by de Wijkerslooth EML, Boerma EG (…) van den Boom AL et 18 al. in Ann Surg
Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.